146828-21-9

Basic information

• Product Name: 2,5-Dimethoxy-2'-nitro-4'-trifluoromethyldiphenylamine
• Synonyms: 2,5-Dimethoxy-2'-nitro-4'-trifluoromethyldiphenylamine
• CAS NO: 146828-21-9
• Molecular Weight: 342.274
• Mol File: 146828-21-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-Dimethoxy-2'-nitro-4'-trifluoromethyldiphenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethoxy-2'-nitro-4'-trifluoromethyldiphenylamine(146828-21-9)
• EPA Substance Registry System: 2,5-Dimethoxy-2'-nitro-4'-trifluoromethyldiphenylamine(146828-21-9)

Safety Data

• Hazardous Substances Data: 146828-21-9(Hazardous Substances Data)

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 102-56-7 2,5-dimethoxyaniline 

Downstream Products

• 146828-44-6 N-(2-nitrophenyl)-1-amino-2-naphthol 
• 153935-09-2 N¹-(2,5-Dimethoxy-phenyl)-4-trifluoromethyl-benzene-1,2-diamine 

Relevant articles and documents

Synthesis and biological activity of the neuronal calcium channel blocker 2-amino-1-(2,5-dimethoxyphenyl)-5-trifluoromethyl benzimidazole (NS-649)

The substituted benzimidazole, NS-649, has been shown to be a blocker of neuronal calcium channels in patch-clamp studies. NS-649 dose-dependently inhibited release of D-aspartate from cerebellar granule neurons. The neuroprotective effect of this compound in vitro and in vivo models of ischemia was demonstrated.