146877-29-4

Upstream product

• 104410-90-4 tert-butyldimethylsilyl trifluoroacetate 
• 103-80-0 phenylacetyl chloride 
• 6728-72-9 3-hydroxy-4-phenylbutanoic acid ethyl ester 
• 718-08-1 ethyl 3-oxo-4-phenylbutyrate 
• 74965-87-0 2,2-dimethyl-5-(2-phenylacetyl)-1,3-dioxane-4,6-dione 
• 146877-28-3 (S)-4-(benzyloxy)-1-phenylbutan-2-ol 
• 100-58-3 phenylmagnesium bromide 
• 146877-18-1 ((S)-1-Benzyl-3-benzyloxy-propoxy)-tert-butyl-dimethyl-silane 

Downstream Products

• 1388181-64-3 (+/-)-tert-butyl((4-chloro-1-phenylbutan-2-yl)oxy)dimethylsilane 
• 1428898-78-5 (±)-3-chloro-4-phenylbutyl 4-methylbenzoate 
• 1428898-50-3 C₁₈H₂₀O₃ 
• 1428898-76-3 (±)-2-chloro-4-((4-methoxybenzyl)oxy)-1-phenylbutane 

Relevant academic research and scientific papers

NRF 2 ACTIVATOR

Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, which are activators of nuclear factor erythroid 2 (NF-E2) -related factor 2 (Nrf2) and are useful to treat diseases caused by oxidative stress, such as neurodegenerative diseases or inflammation. Also provided are methods for their use and production.

Stereocontrolled Total Synthesis of 9(R)-N-BOC-Ahda Methyl Ester

An efficient convergent route to the first total synthesis of 9(R)-N-BOC-Ahda methyl ester, in optically pure form, is described.