146883-83-2Relevant academic research and scientific papers
Fluorinated amino acids: the mechanism of the α-bromo-γ-fluoro-α,β-unsaturated ester amination with ammonia in DMSO
Laskovics, F. M.,Borgne, J. F. Le,Piriou, F.,Wolf, E.
, p. 529 - 540 (2007/10/02)
This work examines the effect of a γ-fluorine substituent on the conversion of an α,β-unsaturated α-bromobutenoate to a trans β,γ-unsaturated γ-fluoro-α-amino acid, by the action of NH3 in DMSO.Employing bromo ester 6 as the substrate, product isolation-i
