146934-35-2

Upstream product

• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 146934-34-1 2,3,4-Tri-O-benzoyl-α-L-rhamnopyranosyl chloride 
• 141020-07-7 C₂₉H₂₆O₉ 
• 101068-99-9 methyl 2,3,4-tri-O-benzoyl α-L-rhamnopyranoside 

Downstream Products

• 146934-40-9 1-(Trimethylsilyl)ethyl 2,4-di-O-benzoyl-3-O-(2,4-di-O-benzoyl-3-O-chloroacetyl-α-L-rhamnopyranosyl)-α-L-rhamnopyranoside 
• 146934-41-0 1-(Trimethylsilyl)ethyl 2,4-di-O-benzoyl-3-O-(2,4-di-O-benzoyl-α-L-rhamnopyranosyl)-α-L-rhamnopyranoside 
• 146934-37-4 2-(Trimethylsilyl)ethyl 2,4-di-O-benzoyl-α-L-rhamnopyranoside 

Relevant academic research and scientific papers

A synthesis of 2-(trimethylsilyl)ethyl α-D-mannopyranoside

The first high yield synthesis is reported of 2-(trimethylsilyl)ethyl α-D-mannopyranoside using 2-O-benzoylated mannosyl donors, as precursors.

Synthesis of tetrasaccharide building block of the O-specific polysaccharide of Shigella dysenteriae type 1

A glycosyl trichloroacetimidate derivative (1) of the tetrasaccharide α-D-Galp-(1→3)-α-D-GlcpNAc-(1→3)-α-L-Rhap-(1→3)-α-L-Rhap was synthesized in a highly stereoselective, stepwise manner, using methyl 1-thioglycosides of L-rhamnose, 2-azido-2-deoxy-D-glucose and D-galactose, as major intermediates. The protecting group scenario in compound 1 permits regioselective deblocking at its 'non-reducing end' unit. Therefore 1 is a suitable intermediate for the preparation of extended fragments of the title polysaccharide.