1469366-69-5Relevant academic research and scientific papers
Visualization and isolation of langerhans islets by a fluorescent probe PiY
Kang, Nam-Young,Lee, Sung-Chan,Park, Sung-Jin,Ha, Hyung-Ho,Yun, Seong-Wook,Kostromina, Elena,Gustavsson, Natalia,Ali, Yusuf,Chandran, Yogeswari,Chun, Hang-Suk,Bae, Myungae,Ahn, Jin Hee,Han, Weiping,Radda, George K.,Chang, Young-Tae
, p. 8557 - 8560 (2013)
Lighting up the pancreas: A pancreatic beta cell selective probe PiY (red, see picture) was developed which stains Langerhans islets in live animals without toxicity or side effects. Through tail-vein injection, PiY allowed for a comparison of the islets between healthy and diabetic mice. PiY also facilitated the isolation of healthy Langerhans islets by using a fluorescence-guided surgical procedure. Copyright
