146941-72-2

Basic information

• Product Name: 3-AMINO-4-BROMO-1-METHYLPYRAZOLE
• Synonyms: BUTTPARK 83\09-100;ART-CHEM-BB B024259;4-BROMO-1-METHYL-1H-PYRAZOL-3-AMINE;3-AMINO-4-BROMO-1-METHYLPYRAZOLE;AKOS B024259;3-Amino-4-bromo-1-methyl-1H-pyrazole;3-Amino-4-bromo-1-methyl-1H-pyrazole 98%;3-Amino-4-bromo-1-methyl-1H-pyrazole, 97+%
• CAS NO: 146941-72-2
• Molecular Formula: C₄H₆BrN₃
• Molecular Weight: 176.01
• Mol File: 146941-72-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 90 °C
• Boiling Point: 274.6°Cat760mmHg
• Flash Point: 119.9°C
• Appearance: /
• Density: 1.91g/cm³
• Vapor Pressure: 0.00535mmHg at 25°C
• Refractive Index: 1.678
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.98±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-4-BROMO-1-METHYLPYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-BROMO-1-METHYLPYRAZOLE(146941-72-2)
• EPA Substance Registry System: 3-AMINO-4-BROMO-1-METHYLPYRAZOLE(146941-72-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-43-22
• Safety Statements: 26-37-36/37
• Hazardous Substances Data: 146941-72-2(Hazardous Substances Data)

Usage

General Description

3-Amino-4-bromo-1-methylpyrazole is a chemical compound with the molecular formula C5H6BrN3. It is a pyrazole derivative and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 3-AMINO-4-BROMO-1-METHYLPYRAZOLE is also known for its high biological activity and is used in the development of potential drugs. Additionally, 3-Amino-4-bromo-1-methylpyrazole has been used in scientific research related to the study of pyrazole derivatives and their pharmacological properties. It is important to handle this chemical with care as it may pose health and environmental hazards if not used or disposed of properly.

InChI:InChI=1/C4H6BrN3/c1-8-2-3(5)4(6)7-8/h2H,1H3,(H2,6,7)

Upstream product

• 1904-31-0 methyl-1 amino-3 pyrazole 

Downstream Products

• 1186230-68-1 N-{[2,4-bis(methyloxy)phenyl]methyl}-4-bromo-1-methyl-1H-pyrazol-3-amine 
• 1089212-38-3 4-bromo-3-(difluoromethyl)-1-methyl-1H-pyrazole 

Relevant articles and documents

Oxidative N—N coupling of N-alkyl-3-aminopyrazoles to azopyrazoles in aqueous solutions of NaOCl and NaOBr

The influence of the structures of N-alkyl-3-aminopyrazoles on their transformation into azopyrazoles on treatment with sodium hypohalogenites was studied. The reaction of 3-aminopyrazoles unsubstituted at position 4 containing donor substituents with neu

Preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

The invention discloses a preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid, and belongs to the technical field of organic synthesis. The preparation method comprises thefollowing steps: reacting N-methyl-3-aminopyrazole as a raw material with bromine/iodine to replace pyrazole at site 4, then carrying out diazotizing and coupling with potassium difluoromethyl trifluoroborate to obtain 4-bromo-3-(difluoromethyl)-1-methyl-1H-pyrazole, then performing Grignard exchange by adopting isopropyl magnesium chloride and the like, and performing reaction with carbon dioxide to obtain 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid. The method is simple and convenient to operate, the total yield of the three steps is as high as 64%, the product purity can reach 99.5% or above, the situation in which isomers exist in a traditional process is avoided, and the method has potential process amplification prospects.