1469438-33-2Relevant academic research and scientific papers
Selective synthesis of polysubstituted dihydroquinolines and α,β-unsaturated amidines by a catalytic reaction of ynamides with ketimines
Kuroda, Yuusuke,Shindoh, Naoya,Takemoto, Yoshiji,Takasu, Kiyosei
, p. 2328 - 2329 (2013/09/02)
Ynamides reacted with benzophenone imines in the presence of triflic imide as a catalyst. Ynamides bearing a sulfonamide moiety gave the corresponding 2-amino-3,4-dihydroquinolines selectively in good to high yields. In contrast, yne-carbamates gave the corresponding α,β-unsaturated amidines exclusively. These methods permit simple preparation of sterically crowded polysubstituted quinolines and α,β-unsaturated amidines. Georg Thieme Verlag Stuttgart. New York.
