146944-27-6

Basic information

• Product Name: (4-BENZYL-MORPHOLIN-2-YL)-ACETIC ACID
• Synonyms: BZL-MORPH-2-ACOH;4-(PHENYLMETHYL)-2-MORPHOLINEACETIC ACID;(4-BENZYL-MORPHOLIN-2-YL)-ACETIC ACID;4-BENZYL-2-MORPHOLINEACETIC ACID;2-(4-BENZYLMORPHOLIN-2-YL)ACETIC ACID;N-BENZYLMORPHOLINE-2-YLACETIC ACID, RACEMATE;Zinc04202805;Zinc04202806
• CAS NO: 146944-27-6
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.28
• Product Categories: Carboxylic Acids;Morpholines & Thiomorpholines;Carboxylic Acids;Morpholines & Thiomorpholines
• Mol File: 146944-27-6.mol

Chemical Properties

• Boiling Point: 391.147 °C at 760 mmHg
• Flash Point: 190.359 °C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-BENZYL-MORPHOLIN-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4-BENZYL-MORPHOLIN-2-YL)-ACETIC ACID(146944-27-6)
• EPA Substance Registry System: (4-BENZYL-MORPHOLIN-2-YL)-ACETIC ACID(146944-27-6)

Safety Data

• Hazardous Substances Data: 146944-27-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(4-Benzyl-morpholin-2-yl)-acetic acid is used as a reactant for the synthesis of 4-sulfonylmorpholine derivatives, which are crucial in developing inhibitors for human 11-β-hydroxy steroid dehydrogenase type 1. These inhibitors have potential applications in treating various medical conditions related to the enzyme's function.
Used in Research and Development:
In the field of research and development, (4-Benzyl-morpholin-2-yl)-acetic acid is utilized as a key compound in the study and understanding of the enzyme human 11-β-hydroxy steroid dehydrogenase type 1. This knowledge can lead to the development of novel therapeutic strategies and treatments for related health issues.

InChI:InChI=1/C13H17NO3/c15-13(16)8-12-10-14(6-7-17-12)9-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H,15,16)

Upstream product

• 57962-45-5 (4-benzylmorpholin-2-yl)acetonitrile 
• 104-63-2 N-Benzylethanolamine 
• 40987-25-5 N-benzyl-2-chloromethylmorpholine 
• 766539-34-8 methyl 2-(4-benzylmorpholine-2-yl)acetate 
• 73933-19-4 ethyl 4-(phenylmethyl)-2-morpholineacetate 

Downstream Products

• 146944-29-8 4-benzyl-2-(((ethoxycarbonyl)amino)methyl)morpholine 
• 135072-27-4 4-benzyl-2-(carbamoylmethyl)morpholine 

Relevant articles and documents

A COMPOUND FOR INHIBITING HUMAN 11-β-HYDROXY STEROID DEHYDROGENASE TYPE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention relates to a novel compound, or a stereoisomer, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) comprising the same. The invention provides a compound, which has excellent activity and solubility and is more efficiently formulated and delivered, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 comprising the same.

Quinolone antimicrobial agents substituted with morpholines at the 7- position. Syntheses and structure-activity relationships

A series of novel 7-substituted 1-cyclopropyl-6,8-difluoro-1,4-dihydro-4- oxo-3-quinolinecarboxylic acids have been prepared and tested for antibacterial activities and for convulsive activities in combination with nonsteroidal antiinflammatory drug. Stru