146944-27-6 Usage
Uses
(4-Benzyl-morpholin-2-yl)-acetic acid (cas# 146944-27-6) is a useful reactant for 4-sulfonylmorpholine derivatives, an inhibitor of human 11-?β-?hydroxy steroid dehydrogenase type 1.
Check Digit Verification of cas no
The CAS Registry Mumber 146944-27-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,9,4 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 146944-27:
(8*1)+(7*4)+(6*6)+(5*9)+(4*4)+(3*4)+(2*2)+(1*7)=156
156 % 10 = 6
So 146944-27-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO3/c15-13(16)8-12-10-14(6-7-17-12)9-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H,15,16)
146944-27-6Relevant articles and documents
A COMPOUND FOR INHIBITING HUMAN 11-β-HYDROXY STEROID DEHYDROGENASE TYPE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
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Page/Page column 45-46, (2012/10/08)
The present invention relates to a novel compound, or a stereoisomer, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) comprising the same. The invention provides a compound, which has excellent activity and solubility and is more efficiently formulated and delivered, and a pharmaceutical composition for human-11-beta-hydroxysteroid dehydrogenase type 1 comprising the same.