146965-08-4

Basic information

• Product Name: C₃₄H₅₉O₃PSi₂
• CAS NO: 146965-08-4
• Molecular Weight: 602.985
• Mol File: 146965-08-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₄H₅₉O₃PSi₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₅₉O₃PSi₂(146965-08-4)
• EPA Substance Registry System: C₃₄H₅₉O₃PSi₂(146965-08-4)

Safety Data

• Hazardous Substances Data: 146965-08-4(Hazardous Substances Data)

Upstream product

• 1733-57-9 ethydiphenylphosphine oxide 
• 146965-02-8 2-Diphenylphosphinoyl-6-hydroxydecan-3-one 
• 104-50-7 gamma-octalactone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 146965-10-8 2-(Diphenyl-phosphinoyl)-decane-3,6-diol 

Downstream Products

• 146965-10-8 (2RS,3SR)-2-Diphenylphosphinoyldecane-3,6-diol 
• 146965-10-8 (2RS,3RS)-2-Diphenylphosphinoyldecane-3,6-diol 

Relevant articles and documents

Stereochemically controlled Synthesis of Unsaturated Alcohols by the Horner-Wittig Reaction

Single isomers (E or Z) of unsaturated alcohols with two to five carbon atoms between the double bond and the OH group may be made by the phosphine oxide version of the Horner-Wittig reaction.Hydroxyalkyldiphenylphosphine oxides react with aldehydes either directly or as silyl ethers to give a moderately Z-selective synthesis, while rearrangement of esters of the same alcohols by acyl transfer or acylation of alkyldiphenylphosphine oxides with lactones gives hydroxy ketones whose reduction and elimination leads to an E-selective synthesis.In most cases, separation of the diastereoisomers of the Horner-Wittig intermediates leads to the preparation of pure E- or Z-alkenols.