146978-48-5

Basic information

• Product Name: Moxilubant
• Synonyms: Moxilubant;Moxilubant [inn]
• CAS NO: 146978-48-5
• Molecular Formula: C₂₆H₃₇N₃O₄
• Molecular Weight: 455.595
• Mol File: 146978-48-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 625.5±65.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• PKA: 12.50±0.50(Predicted)
• CAS DataBase Reference: Moxilubant(CAS DataBase Reference)
• NIST Chemistry Reference: Moxilubant(146978-48-5)
• EPA Substance Registry System: Moxilubant(146978-48-5)

Safety Data

• Hazardous Substances Data: 146978-48-5(Hazardous Substances Data)

Usage

Uses

Antirheumatic; anti-inflammatory (nonsteroidal); antipsoriatic.

InChI:InChI=1/C26H37N3O4/c1-18(2)29(19(3)4)26(30)21-11-14-23(24(17-21)31-5)33-16-8-6-7-15-32-22-12-9-20(10-13-22)25(27)28/h9-14,17-19H,6-8,15-16H2,1-5H3,(H3,27,28)

Upstream product

• 111-29-5 1 ,5-pentanediol 
• 15535-98-5 p-hydroxybenzamidine 
• 99865-83-5 4-hydroxy-3-methoxy-benzoic acid allyl ester 
• 108-18-9 diisopropylamine 

Downstream Products

• 146978-40-7 4-[5-[4-(acetyliminoaminomethyl)phenoxy]pentyloxy]-3-methoxy-N,N-bis(1-methylethyl)benzamide 

Relevant articles and documents

A linker for amidines in solid phase synthesis

A range of linkers for the important amidine pharmacophore, cleavable using acid or light have been developed for use in library synthesis. The utility of these linkers is demonstrated by the solid phase synthesis of the Novartis (ex-Ciba) phase II compou

AMIDINO COMPOUNDS, THEIR MANUFACTURE AND METHODS OF TREATMENT

The invention relates to the compounds of the formula STR1 wherein the C(=NH)--NHR 3 group may be in tautomeric or isomeric form, and phamaceutically acceptable salts thereof. The compounds are useful as selective LTB 4 receptor antagonists.