146983-20-2

Upstream product

• 98837-36-6 methyl 3-hydroxy-2-methylenebutyrate 
• 33935-64-7 methyl 2-(bromomethyl)-2-butenoate 
• 28127-64-2 methyl (2E)-2-(hydroxymethyl)-2-butenoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1321530-46-4 (S,E)-tert-butyl((2-ethyl-4-iodobut-3-en-1-yl)oxy)diphenylsilane 
• 1321530-55-5 (S)-methyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)butanoate 
• 1321530-52-2 (R)-methyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)butanoate 
• 1321530-56-6 (R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)butanal 
• 147059-00-5 methyl(1S,2S,5R)-4-<<(tert-butyldiphenylsilyl)oxy>methyl>-1-acetoxy-5-methyl-2-<2'-methyl-3'-<(tert-butyldimethylsilyl)oxy>-1'(E)-propen-1'-yl>-3-cyclohexene-1-carboxylate 
• 147058-91-1 methyl (1S,2S,5R)-4-<<(tert-butyldiphenylsilyl)oxy>methyl>-1-acetoxy-5-methyl-2-<2'-methyl-3'-<(tert-butyldimethylsilyl)oxy>-1'(E)-propen-1'yl>-3-cyclohexene-1-carboxylate 
• 147058-98-8 (E)-3-[(2R,5S,6R,9S)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-2-methyl-acrylic acid ethyl ester 
• 146983-25-7 (E)-3-[(2R,5S,6S,9R)-2-tert-Butyl-8-(tert-butyl-diphenyl-silanyloxymethyl)-9-methyl-4-oxo-1,3-dioxa-spiro[4.5]dec-7-en-6-yl]-2-methyl-acrylic acid ethyl ester 
• 146983-28-0 methyl (1S,2R,5S)-4-<<(tert-butyldiphenylsilyl)oxy>methyl>-1-hydroxy-5-methyl-2-<2'-methyl-3'-<(tert-butyldimethylsilyl)oxy>-1'(E)-propen-1'-yl>-3-cyclohexene-1-carboxylate 

Relevant academic research and scientific papers

Diastereoselective synthesis of the top half of kijanolide

A highly diastereoselective synthesis of the top half (4) of kijanolide is described. The key step is the exo and diastereoface selective Diels-Alder reaction of triene 6 and chiral dienophile 6.

Indium-mediated allylation of carbonyl compounds with an allylic bromide in aqueous media: Anomalous syn-diastereoselectivity regardless of allylic bromide geometry

Anomalous syn-diastereoselectivity of indium-mediated coupling of aldehydes with bromides Z-3b and E-3b is reported. The reaction afforded high syn selectivity regardless of the allylic bromide geometry. Preliminary studies on the enantioselective indium-mediated allylation were attempted and found to give the desired products in moderate yield with high syn selectivity and enantioselectivity.

A Highly Diastereo- and Enantioselective Synthesis of the Top Half of Kijanolide

A highly diastereo- and enantioselective synthesis of spirotetronate 4 corresponding to the top half of kijanolide is reported.This synthesis features the novel exo-selective Diels-Alder reaction of triene 6 and the chiral, nonracemic dienophiles (R)-7 an