1469874-76-7Relevant academic research and scientific papers
Zinc mediated activation of terminal alkynes: Stereoselective synthesis of alkynyl glycosides
Tatina, Madhu Babu,Kusunuru, Anil Kumar,Yousuf, Syed Khalid,Mukherjee, Debaraj
, p. 7900 - 7903 (2014)
Zinc mediated alkynylation reaction was studied for the preparation of C-glycosides from unactivated alkynes. Different glycosyl donors such as glycals and anomeric acetates were tested towards an alkynyl zinc reagent obtained from alkynes using zinc dust
TMSOTf mediated stereoselective synthesis of α-C-glycosides from unactivated aryl acetylenes
Chen, Heshan,Luo, Xiaosheng,Qiu, Saifeng,Sun, Wengjie,Zhang, Jianbo
, p. 13 - 20 (2017/02/05)
A metal free and highly stereoselective procedure for the synthesis of 2,3-unsaturated-C-glycosides has been developed between glycals and unactivated aryl acetylenes in the presence of TMSOTf through a triflated C-vinyl glycosides intermediate. The flexi
A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes
Devari, Shekaraiah,Kumar, Manjeet,Deshidi, Ramesh,Rizvi, Masood,Shah, Bhahwal Ali
supporting information, p. 2649 - 2653 (2015/02/19)
A novel metal-free strategy for a rapid and α-selctive C-alkynylation of glycals was developed. The reaction utilizes TMSOTf as a promoter to generate in situ trimethylsilylacetylene for C-alkynylation. Thanks to this methodology, we can access C-glycosid
Transformation of Glycals into α,β,γ,δ-Conjugated Chirons under Metal-Free Conditions
Madhubabu, Tatina,Yousuf, Syed Khalid,Kusunuru, Anil Kumar,Mukherjee, Debaraj
supporting information, p. 7333 - 7338 (2016/02/19)
A diastereoselective, metal-free, one-pot domino synthetic strategy was developed for the transformation of glycals into new chiral scaffolds. Optimization of the reaction conditions to exclude normal Ferrier products, characterization of the new entities
Copper mediated stereoselective synthesis of C-glycosides from unactivated alkynes
Kusunuru, Anil Kumar,Tatina, Madhubabu,Yousuf, Syed Khalid,Mukherjee, Debaraj
supporting information, p. 10154 - 10156 (2013/10/22)
A highly stereoselective rapid C-glycosylation reaction has been developed between glycal and unactivated alkynes in the presence of coppertriflate and ascorbic acid at low catalyst loading and at room temperature. A wide variety of glycals and aryl acetylenes participate in the reaction smoothly. TfOH generated during the reduction of Cu(OTf)2 by ascorbic acid may be the active catalyst for the glycosylation. The Royal Society of Chemistry 2013.
