146993-07-9

Upstream product

• 763054-78-0 1-[2-(2-methoxyphenoxy)-ethyl]piperidin-4-amine 
• 22536-66-9 2-chloro-4-pyrimidinecarboxamide 
• 147007-76-9 8-[2-(2-Methoxyphenoxy)ethyl]-1,4-dioxa-8-azaspiro-[4.5]decane 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 4463-59-6 2-(methoxyphenoxy)ethylbromide 
• 78-93-3 butanone 

Relevant academic research and scientific papers

2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTICS

A compound which is a 2-aminopyrimidine carboxamide derivative represented by formula (I) STR1 in which X represents hydrogen, fluorine, chlorine, methyl, 1-methylethyl or methoxy, with the proviso that more than one substituent X may be present in which case each X may be the same or different,n represents 2 or 3, m represents 1, in which case p represents 1, or else m represents 0, in which case p represents 2,q represents 0 or 1, andR 1 represents a hydrogen atom; or a pharmaceutically acceptable acid addition salt thereof. A compound of formula (I) has α 1-adrenergic receptor antagonist activity and is useful as a therapeutic substance.