1470-38-8 Usage
Uses
Used in Pharmaceutical Industry:
2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione is used as a therapeutic agent for its anti-inflammatory properties, helping to alleviate inflammation in various conditions.
2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione is used as an antioxidant agent for its ability to neutralize harmful free radicals, thereby protecting cells from oxidative damage.
Used in Anticancer Applications:
2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione is used as a potential cancer treatment agent due to its capacity to inhibit the growth of certain cancer cells, making it a candidate for further research and development in oncology.
Used in Neurodegenerative Disorder Management:
2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione is used as a neuroprotective agent for its potential benefits in managing conditions such as Alzheimer's disease and other neurodegenerative disorders, due to its neuroprotective effects.
Overall, 2-(3,4-Dimethoxyphenyl)-1H-indene-1,3(2H)-dione, or deoxyandrographolide, shows promise as a versatile therapeutic agent across multiple medical fields and requires further investigation to fully explore its potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1470-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,7 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1470-38:
(6*1)+(5*4)+(4*7)+(3*0)+(2*3)+(1*8)=68
68 % 10 = 8
So 1470-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H14O4/c1-20-13-8-7-10(9-14(13)21-2)15-16(18)11-5-3-4-6-12(11)17(15)19/h3-9,15H,1-2H3
1470-38-8Relevant academic research and scientific papers
Hypolipidemic Activity of Indan-1,3-dione Derivatives in Rodents
Murthy, A. R.,Wyrick, S. D.,Hall, I. H.
, p. 1591 - 1596 (2007/10/02)
A series of 2-substituted indan-1,3-dione derivatives, including alkyl (C-1-C-5), mono- and disubstituted phenyl, and other 2-aryl derivatives, were tested for hypolipidemic activity of CF1 male mice at 20 mg/kg per day.These derivatives reduced both serum cholesterol and triglycerides after 16 days of administration intraperitoneally. 2-(4-Methoxyphenyl)indan-1,3-dione was one of the more active compounds with 41percent reduction of serum cholesterol and 58percent reduction of serum triglyceride levels on day 16.This activity was confirmed in the rat after oral administration. 2-(2-Methylphenyl)- and 2-(4-chlorophenyl)indan-1,3-dione were effective in reducing serum triglyceride levels 58percent and 53percent, respectively, in mice.Serum cholesterol on day 16 was effectively reduced 46percent by 2-(2,4-dimethylphenyl)indan-1,3-dione.The indan-1,3-dione derivatives were more effective than clofibrate in lowering lipid levels in mice.A more detailed study on the effects of 2-(4-methoxyphenyl)indan-1,3-dione demonstrated that key enzymes in the de novo synthesis of lipids were inhibited by the drug lowering tissue levels of lipids but raising those in the feces.The alterations in lipid content of rat lipoprotein fractions by the drug appeared favorable.
