147007-80-5Relevant academic research and scientific papers
2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTICS
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, (2008/06/13)
A compound which is a 2-aminopyrimidine carboxamide derivative represented by formula (I) STR1 in which X represents hydrogen, fluorine, chlorine, methyl, 1-methylethyl or methoxy, with the proviso that more than one substituent X may be present in which case each X may be the same or different,n represents 2 or 3, m represents 1, in which case p represents 1, or else m represents 0, in which case p represents 2,q represents 0 or 1, andR 1 represents a hydrogen atom; or a pharmaceutically acceptable acid addition salt thereof. A compound of formula (I) has α 1-adrenergic receptor antagonist activity and is useful as a therapeutic substance.
