1470522-09-8

Basic information

• Product Name: C₁₅H₂₃NO₄
• Synonyms: C₁₅H₂₃NO₄
• CAS NO: 1470522-09-8
• Molecular Weight: 281.352
• Mol File: 1470522-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₃NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₃NO₄(1470522-09-8)
• EPA Substance Registry System: C₁₅H₂₃NO₄(1470522-09-8)

Safety Data

• Hazardous Substances Data: 1470522-09-8(Hazardous Substances Data)

Upstream product

• 102421-43-2 N-((1,1-dimethylethyl)oxycarbonyl)-3,4-dimethoxyaniline 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 1449378-26-0 (3,4-dimethoxy-benzyl)-carbamic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 6315-89-5 3,4-dimethoxyaniline 
• 5763-61-1 3,4-dimethoxybenzylamine 

Downstream Products

• 63-64-9 N-methylveratrylamine 
• 62-71-5 5-[(3,4-dimethoxy-benzyl)-methyl-amino]-2-(3,4-dimethoxy-phenyl)-2-isopropylpentanenitrile 

Relevant articles and documents

Synthesis of new verapamil analogues and their evaluation in combination with rifampicin against Mycobacterium tuberculosis and molecular docking studies in the binding site of efflux protein Rv1258c

New verapamil analogues were synthesized and their inhibitory activities against Mycobacterium tuberculosis H37Rv determined in vitro alone and in combination with rifampicin (RIF). Some analogues showed comparable activity to verapamil and exhibited better synergies with RIF. Molecular docking studies of the binding sites of Rv1258c, a M. tuberculosis efflux protein previously implicated in intrinsic resistance to RIF, suggested a potential rationale for the superior synergistic interactions observed with some analogues.