147059-46-9 Usage
General Description
Rocaglaol is a naturally occurring chemical compound found in several plant species, including species of the Aglaia genus. It has been identified as a potent inhibitor of mitochondrial complex I, an enzyme that plays a crucial role in the production of ATP, the body's main energy source. Rocaglaol has been studied for its potential anti-cancer properties, as it is believed to induce cell death in cancerous cells by disrupting their energy production. Research on Rocaglaol is ongoing, and its potential uses in cancer therapy and other medical applications are under investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 147059-46-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,0,5 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 147059-46:
(8*1)+(7*4)+(6*7)+(5*0)+(4*5)+(3*9)+(2*4)+(1*6)=139
139 % 10 = 9
So 147059-46-9 is a valid CAS Registry Number.
147059-46-9Relevant articles and documents
Total synthesis of (±)-rocaglamide and some aryl analogues
Dobler, Markus R,Bruce, Ian,Cederbaum, Fredrik,Cooke, Nigel G,Diorazio, Louis J,Hall, Roger G,Irving, Ed
, p. 8281 - 8284 (2007/10/03)
The insecticidal activity found for rocaglamide and its congeners, prompted us to establish a short and efficient synthesis of the natural product and some synthetic 'halo-aryl' analogues. Pd-catalysed cross-coupling reactions of the bromo analogue were then explored in order to gain a suitable access to a broad range of unnatural analogues. The key step of our approach is a keto-aldehyde acyloin ring-closure followed by a Stiles carboxylation.
Synthesis of the novel anti-leukaemic tetrahydrocyclopenta[b]benzofuran, rocaglamide
Davey,Schaeffer,Taylor
, p. 1137 - 1139 (2007/10/02)
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