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Usage

Uses

Used in Pharmaceutical Industry:
2-(4-(1,2,2-triphenylvinyl)phenoxy)acetic acid is used as a pharmaceutical intermediate for the synthesis of various drugs and active pharmaceutical ingredients. Its unique chemical structure allows for the development of new compounds with potential therapeutic effects.
Used in Chemical Industry:
In the chemical industry, 2-(4-(1,2,2-triphenylvinyl)phenoxy)acetic acid can be utilized as a building block or a precursor in the synthesis of complex organic molecules. Its triphenylvinyl group provides opportunities for further functionalization and the creation of novel chemical entities with specific properties.
Further Research:
Due to the novelty of 2-(4-(1,2,2-triphenylvinyl)phenoxy)acetic acid, further research is required to fully explore its potential uses and effects. This includes investigating its biological activity, stability, and reactivity, as well as its potential applications in various fields such as materials science, agrochemicals, and environmental chemistry.

Upstream product

• 76115-06-5 1-(4'-hydroxyphenyl)-1,2,2-triphenylethylene 
• 70592-05-1 (2-(4-methoxyphenyl)ethene-1,1,2-triyl)tribenzene 
• 76115-05-4 1-(4'-methoxyphenyl)-1,2,2-triphenylethanol 
• 611-94-9 4-Methoxybenzophenone 
• 101-81-5 Diphenylmethane 

Relevant academic research and scientific papers

A cascade enzymatic reaction activatable gemcitabine prodrug with an AIE-based intracellular light-up apoptotic probe for: In situ self-therapeutic monitoring

A targeted cathepsin B-activatable gemcitabine prodrug with caspase-3 specific light-up tetraphenylene (TPE) as an apoptotic probe based on aggregation-induced emission (AIE) properties was designed for in situ self-therapeutic monitoring of pancreatic ca

A fluorescent switchable AIE probe for selective imaging of dipeptidyl peptidase-4 in vitro and in vivo and its application in screening DPP-4 inhibitors

A novel fluorescent probe for in vitro and in vivo imaging of dipeptidyl peptidase-4 (DPP-4) was designed and synthesized. This probe is successfully utilized to screen DPP-4 inhibitors in living 3T3-L1 cells and zebrafish, which provides a novel approach

AIE Fluorescent Gelators with Thermo-, Mechano-, and Vapochromic Properties

A series of aggregation-induced emission (AIE) fluorescent gelators (TPE-Cn-Chol) were synthesized by attaching tetraphenylethylene (TPE) to cholesterol through an alkyl chain. The properties of the gel, nano-/microaggregate, and condensed phas

Fluorescence turn-on chemosensor for highly selective and sensitive detection and bioimaging of al3+ in living cells based on ion-induced aggregation

Herein, a new fluorescence turn-on chemosensor 2-(4-(1,2,2-triphenylvinyl)phenoxy)acetic acid (TPE-COOH) specific for Al3+ was presented by combining the aggregation-induced-emission (AIE) effect of tertaphenylethylene and the complexation capability of carboxyl. The introduction of carboxylic group provides the probe with good water-solubility which is important for analyzing biological samples. The recognition toward Al3+ induced the molecular aggregation and activated the blue fluorescence of the TPE core. The high selectivity of the probe was demonstrated by discriminating Al3+ over a variety of metal ions in a complex mixture. A detection limit down to 21.6 nM was determined for Al3+ quantitation. Furthermore, benefiting from its good water solubility and biocompatibility, imaging detection and real-time monitoring of Al3+ in living HeLa cells were successfully achieved. The AIE effect of the probe enables high signal-to-noise ratio for bioimaging even without multiple washing steps. These superiorities make this probe a great potential for the functional study and analysis of Al3+ in complex biosystems.

A novel aggregation-induced emission based fluorescent probe for an angiotensin converting enzyme (ACE) assay and inhibitor screening

A 'turn-on' fluorescent probe based on aggregation-induced emission (AIE) has been developed. It exhibits excellent selectivity and sensitivity for monitoring angiotensin converting enzyme (ACE) activity both in solutions and in living cells as well as fo

Spontaneous chiral self-assembly of achiral AIEgens into AIEgen-silica hybrid nanotubes

Antipodal chiral AIEgen-silica hybrid mesostructures were fabricated by spontaneous chiral self-assembly of the achiral amphiphilic AIEgen 2-[4-(1,2,2-triphenylethenyl)phenoxy]-acetic acid via a co-structure directing route in the absence of any symmetry-

The rational design of a gemcitabine prodrug with AIE-based intracellular light-up characteristics for selective suppression of pancreatic cancer cells

An enzyme and reduction-activatable gemcitabine prodrug (TPE-GEM-RGD) with aggregation-induced emission (AIE) properties was designed for targeted and image-guided cancer therapy. TPE-GEM-RGD was successfully used for intracellular light-up imaging and gl