147148-58-1

Upstream product

• 147148-57-0 1-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-(N-t-butoxy carbonylamino)-3,3-diphenylpropane 
• 92646-33-8 2-amino-3,3-diphenyl-1-propanol 
• 107202-37-9 (1-hydroxymethyl-2,2-diphenyl-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 156101-79-0 5-[((N-(1-((3,5-Bis(trifluoromethyl)phenyl) methyloxy)-3,3-diphenylprop-2-yl)-N-methyl)amino)methyl]-2,3-dihydro-4H-1,2,4-triazol-3-one 

Relevant academic research and scientific papers

3,3-diphenyl prop-2-yl amino acid derivatives and their use as tachykinin antagonists

Compounds of formula (I), or a salt or prodrug thereof, wherein R1 represents H, C1-4 alkyl or CH2 COOH; R2 represents H or C1-4 alkyl, with the proviso that R1 and R2 are not both H; R3 and R4 each independently rely resent H, C1-, alkyl. C2-6 alkenyl C1-6 alkoxy, halo or trifluoromethyl; A1, A2, A3, and A4 each independently represent H, C1-6 alkyl, C1-6 alkenyl, C1-6 alkoxy, halo or trifluoromethyl; and A5 and A6 each independently represent H or C1-4 are tachykinin antagonists useful STR1

2/3-(heterocyclic alkyl amino)-1-(subst.-phenyl-methoxy)-ethanes/propanes as tachykinin-receptor antagonists

Compounds of formula (I), and salts and prodrugs thereof, wherein Q represents phenyl or benzhydryl; X and Y each represent H or X and Y together form a group =0; Z is O, S or NR 8 (R 8 is H or C 1-6 alkyl); R 1 is H, optionally substituted C 1-6 alkyl, p