14716-91-7

Usage

Uses

Used in Pharmaceutical Research:
(3-Propyl-isoxazol-5-yl)-methanol is used as a building block for the synthesis of various bioactive compounds for the development of new drugs.
Used in Chemical Biology and Medicinal Chemistry:
(3-Propyl-isoxazol-5-yl)-methanol is used as a research compound to study its potential pharmacological properties and explore its applications in the treatment of various diseases and disorders.
Used in Drug Development:
(3-Propyl-isoxazol-5-yl)-methanol is used as a starting material for the development of new drugs with potential therapeutic properties.

Upstream product

• 41542-29-4 N-hydroxybutyrimidoyl chloride 
• 107-19-7 propargyl alcohol 
• 627-05-4 1-nitrobutane 
• 5775-75-7 (E)-butanal oxime 

Relevant academic research and scientific papers

A method for generating nitrile oxides from nitroalkanes: A microwave assisted route for isoxazoles

A convenient route has been developed for generation of nitrile oxides in situ from nitroalkanes under very mild conditions using microwave irradiation, using 4-(4,6-dimethoxy[1,3,5]triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) and DMAP as catalyst.

A strategic alternative to solid phase synthesis: Preparation of a small isoxazoline library by 'fluorous synthesis'

The preparation of a highly fluorinated silyl group and its use as a 'fluorous label' are described. Allyl and propargyl alcohols are rendered fluorous upon attachment to the fluorous label. Cycloaddition of the fluorous dipolarophiles to nitrile oxides provides the corresponding isoxazol(in)es which are purified by simple liquid-liquid extractions. After detachment of the label and renewed extraction, the organic isoxazol(in)es are obtained. This new fluorous methodology allows the preparation of isoxazol(in)es in high purities without using chromatography.