1472-75-9 Usage
Uses
Used in Pharmaceutical Applications:
(5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one is used as a potential therapeutic agent for its antitumor and cytotoxic properties. (5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one's unique molecular structure and pharmacological effects make it a candidate for further research and development in the field of oncology.
Used in Chemical Research:
In the field of chemical research, (5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one serves as a subject for studying the structure-activity relationship of crinanone alkaloids. Its unique tetracyclic ring system and lactone ring provide insights into the design and synthesis of novel compounds with potential biological activities.
Used in Drug Development:
(5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one is utilized in drug development as a lead compound for the creation of new pharmaceuticals targeting cancer treatment. Its cytotoxic effects against tumor cells make it a promising starting point for the development of more effective and targeted cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1472-75-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,7 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1472-75:
(6*1)+(5*4)+(4*7)+(3*2)+(2*7)+(1*5)=79
79 % 10 = 9
So 1472-75-9 is a valid CAS Registry Number.
1472-75-9Relevant academic research and scientific papers
Synthesis and antimalarial activity of new haemanthamine-type derivatives
Cedron, Juan C.,Gutierrez, David,Flores, Ninoska,Ravelo, Angel G.,Estevez-Braun, Ana
, p. 5464 - 5472 (2012/10/30)
Thirty one derivatives were prepared from the natural alkaloids haemanthamine (1), haemanthidine (2) and 11-hydroxyvittatine (3). They were evaluated for their in vitro antimalarial activity against chloroquine-sensitive strains of Plasmodium falciparum and some structure-activity relationships were outlined. For haemanthamine derivatives having a methoxy group at C-3, the presence of a free hydroxyl group at C-11 is important for the activity. The double bond at C-1-C-2 plays also an important role to achieve good inhibitory activity. Compound 35 with two nicotinate groups at C-3 and at C-11 was the most active compound with a IC50 = 0.8 ± 0.06 μM.
