1472640-86-0 Usage
Uses
Given the provided materials do not specify any particular applications for (2-phenylpiperidin-1-yl)(4-(3′-(piperidine-1-carbonyl)-[1,1′-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)methanone, it is not possible to list its uses accurately. However, based on its structure, one could hypothesize potential uses in various industries such as pharmaceuticals, materials science, or chemical research, pending further research and development.
If future research were to identify specific applications, the uses could be listed as follows:
Used in Pharmaceutical Industry:
(2-phenylpiperidin-1-yl)(4-(3′-(piperidine-1-carbonyl)-[1,1′-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)methanone could be used as a pharmacological agent for [specific medical condition or treatment] due to its potential to interact with [specific receptors or enzymes].
Used in Materials Science:
In the field of materials science, (2-phenylpiperidin-1-yl)(4-(3′-(piperidine-1-carbonyl)-[1,1′-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)methanone might be utilized as a component in the development of [specific type of material] designed for [intended application], owing to its unique structural properties.
Used in Chemical Research:
As a complex synthetic compound, (2-phenylpiperidin-1-yl)(4-(3′-(piperidine-1-carbonyl)-[1,1′-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)methanone could serve as a subject of study in chemical research for understanding [specific chemical interactions or reactions], contributing to the advancement of [related field of chemistry].
Check Digit Verification of cas no
The CAS Registry Mumber 1472640-86-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,7,2,6,4 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1472640-86:
(9*1)+(8*4)+(7*7)+(6*2)+(5*6)+(4*4)+(3*0)+(2*8)+(1*6)=170
170 % 10 = 0
So 1472640-86-0 is a valid CAS Registry Number.
1472640-86-0Relevant academic research and scientific papers
Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)
Hsu, Ku-Lung,Tsuboi, Katsunori,Chang, Jae Won,Whitby, Landon R.,Speers, Anna E.,Pugh, Holly,Cravatt, Benjamin F.
, p. 8270 - 8279 (2013/12/04)
α/β-Hydrolase domain containing 6 (ABHD6) is a transmembrane serine hydrolase that hydrolyzes the endogenous cannabinoid 2- arachidonoylglycerol (2-AG) to regulate certain forms of cannabinoid receptor-dependent signaling in the nervous system. The full spectrum of ABHD6 metabolic activities and functions is currently unknown and would benefit from selective, in vivo-active inhibitors. Here, we report the development and characterization of an advanced series of irreversible (2-substituted)- piperidyl-1,2,3-triazole urea inhibitors of ABHD6, including compounds KT182 and KT203, which show exceptional potency and selectivity in cells (-1), act as systemic and peripherally restricted ABHD6 inhibitors, respectively. We also describe an orally bioavailable ABHD6 inhibitor, KT185, that displays excellent selectivity against other brain and liver serine hydrolases in vivo. We thus describe several chemical probes for biological studies of ABHD6, including brain-penetrant and peripherally restricted inhibitors that should prove of value for interrogating ABHD6 function in animal models.
