147290-11-7

Basic information

• Product Name: FMOC-ORN(ALOC)-OH
• Synonyms: FMOC-L-ORN(ALLOC)-OH;N-α-Boc-N-δ-allyloxycarbonyl-L-ornithine;nα-fmoc-nδ-alloc-l-ornithine;N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-N--ALLYLOXYCARBONYL-L-ORNITHINE;NDELTA-Allyloxycarbonyl-NALPHA-9-fluorenylmethoxycarbonyl-L-ornithine;Fmoc-L-Orn(Aloc)-OH;N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-N5-[(2-PROPENYLOXY)CARBONYL]-L-ORNITHINE;Nδ-Alloc-Nα-Fmoc-L-ornithine
• CAS NO: 147290-11-7
• Molecular Formula: C₂₄H₂₆N₂O₆
• Molecular Weight: 438.47
• Product Categories: chiral;Amino Acids
• Mol File: 147290-11-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 683.9 °C at 760 mmHg
• Flash Point: 367.4 °C
• Appearance: /Solid
• Density: 1.255 g/cm³
• Vapor Pressure: 1.21E-19mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: 2-8°C
• PKA: 3.85±0.21(Predicted)
• CAS DataBase Reference: FMOC-ORN(ALOC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-ORN(ALOC)-OH(147290-11-7)
• EPA Substance Registry System: FMOC-ORN(ALOC)-OH(147290-11-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 147290-11-7(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C24H26N2O6/c1-2-14-31-23(29)25-13-7-12-21(22(27)28)26-24(30)32-15-20-18-10-5-3-8-16(18)17-9-4-6-11-19(17)20/h2-6,8-11,20-21H,1,7,12-15H2,(H,25,29)(H,26,30)(H,27,28)/t21-/m0/s1

Relevant articles and documents

Synthesis method of double different protected amino acids

The invention relates to a synthesis method of double different protected amino acids.The technical problems of harsh reaction conditions, inapplicability of production enlarging and the like in an existing synthesis method are mainly solved. According to the technical scheme, the synthesis method of double different protected amino acids comprises the following steps: one of Boc20, Alloc-Cl or Cbz-Osuis added to amino alcohol under the action of an alkaline reagent to obtain a compound 1; the compound 1 reacts with methanesulfonyl chloride or paratoluensulfonyl chloride to obtain an intermediate, then a halide is added into acetone, heating and refluxing are executed to obtain a compound 2; the compound 2 is condensed with diethyl acetamidomalonate under the action of an alkaline agent togenerate a compound 3; the compound 3 is dissolved in alcohol and water, an inorganic base is added, heating, hydrolyzing and decarboxylating are executed to obtain a compound 4; acetylase is added into deionized water to obtain a compound 5 through enzymolysis; amino acid protection is executed, wherein one of Fmoc-Osu, Cbz-OSu, Alloc-Cl or Boc20 is added into thecompound 5 under the action of an alkaline agent to generatea target compound A.