147291-70-1

Upstream product

• 2498-50-2 4-aminobenzamidine dihydrochloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 207726-11-2 {[4-(Benzyloxycarbonylamino-imino-methyl)-phenylcarbamoyl]-methyl}-carbamic acid tert-butyl ester 
• 147291-24-5 {8-[4-(benzyloxycarbonylamino-imino-methyl)-phenylcarbamoyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-2-yl}-acetic acid methyl ester 
• 147290-89-9 methyl (R,S)-8-[[[4-(aminoiminomethyl)phenyl]amino]-carbonyl]-1,2,4,5-tetrahydro-3-oxo-4-(2-phenylethyl)-3H-1,4-benzodiazepine-2-acetate 
• 1453097-83-0 C₄₉H₅₇N₅O₈Si 
• 147290-88-8 methyl (R,S)-8-[[[4-[N-(benzyloxycarbonyl)-aminoiminomethyl]phenyl]amino]carbonyl]-1,2,4,5-tetrahydro-3-oxo-4-(2-phenylethyl)-3H-1,4-benzodiazepine-2-acetate 
• 161014-59-1 methyl (R,S)-8-chlorocarbonyl-1,2,4,5-tetrahydro-3-oxo-4-(2-phenylethyl)-3H-1,4-benzodiazepine-2-acetate 
• 207726-13-4 [(4S,7S)-5-({[(4-{Amino-[(Z)-benzyloxycarbonylimino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl]-acetic acid methyl ester 
• 207726-14-5 [(4S,7S)-5-({[(4-{Amino-[(Z)-benzyloxycarbonylimino]-methyl}-phenylcarbamoyl)-methyl]-carbamoyl}-methyl)-3,6-dioxo-2,5-diaza-tricyclo[6.2.2.0^2,7]dodec-4-yl]-acetic acid 
• 207726-12-3 {[4-(2-Amino-acetylamino)-phenyl]-imino-methyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Substituted phenylamidines

Phenylamidines of the formula (I) wherein: R6is a C5-12-alkyloxycarbonyl group, and R7is a hydrogen atom, or a C1-8-alkyl, C4-7-cycloalkyl, phenyl-C1-4-alkyl, or R8—CO—OCHR9

Substituted benzimazoles which inhibit platelet aggrecation

This invention relates to compounds of the formula: STR1 which are effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.

A Constrained Diketopiperazine as a New Scaffold for the Synthesis of Peptidomimetics

As a new scaffold for peptidomimetic synthesis, a highly constrained bifunctional diketopiperazine, 4, has been prepared by smooth N-alkylation with tert-butyl bromoacetate. As a first application, we describe herein the synthesis of new peptidomimetics of the Arg-Gly-Asp (RGD) sequence. The product 30, which shows a selective platelet-aggregation inhibiting activity, can be used as a lead for the preparation of more potent products.