1473-60-5

Basic information

• Product Name: N-salicylidene-3-aminocoumarin
• Synonyms: N-salicylidene-3-aminocoumarin
• CAS NO: 1473-60-5
• Molecular Formula: C₁₆H₁₁NO₃
• Molecular Weight: 265.26
• Mol File: 1473-60-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 503.6°Cat760mmHg
• Flash Point: 258.3°C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 2.88E-10mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: N-salicylidene-3-aminocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: N-salicylidene-3-aminocoumarin(1473-60-5)
• EPA Substance Registry System: N-salicylidene-3-aminocoumarin(1473-60-5)

Safety Data

• Hazardous Substances Data: 1473-60-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H11NO3/c18-14-7-3-1-6-12(14)10-17-13-9-11-5-2-4-8-15(11)20-16(13)19/h1-10,17H/b12-10+

Upstream product

• 1635-31-0 aminocoumarine 
• 90-02-8 salicylaldehyde 
• 616-34-2 methoxycarbonylmethylamine 
• 779-30-6 3-acetamidocoumarin 
• 623-33-6 glycine ethyl ester hydrochloride 

Downstream Products

• 134268-98-7 Boc-Phe-NH-c 
• 112517-46-1 C₂₂H₁₅N₃O₄ 
• 112517-44-9 C₂₂H₁₅N₃O₃ 
• 112517-45-0 C₂₂H₁₄ClN₃O₃ 
• 97472-95-2 3-salicylaminocoumarin 
• 709-16-0 2-hydroxy-phenylalanine 
• 1635-31-0 aminocoumarine 
• 939-19-5 3-Hydroxy-cumarin 
• 112517-48-3 C₂₂H₁₃Cl₂N₃O₃ 
• 112517-47-2 C₂₂H₁₃Cl₂N₃O₃ 

Relevant articles and documents

A novel coumarinyl scaffold as metal ion sensor towards spectrophotometric detection of Cu2+, Ni2+ and Zn2+ ion

A new series of coumarin based metal ion sensors have been prepared devising a green protocol involving ethyl-(L)-lactate as a polar solvent. These compounds either selectively bind with specific transitional metal ions or form complexes with specific photophysical character when subjected to absorption spectroscopy. The derived Schiff's bases quantitatively bind with metal ions to form 1:1 complexes making them a useful tool for qualitative estimation of metal ions in biological as well as organic systems.

Synthesis of 3-[α-(3-Chloro-2-oxo-4-substituted-phenyl/furfuryl-1-azetidinyl)]-2H-1- benzopyran-2-ones and 3-[α-(2-Substituted-phenyl/furfurylthiazolidiznyl)]-2H-1-benzopyran-2-ones as C.N.S. -active Agents

Reaction of 3-substituted-phenylidine/furfurylidineamino-2H-1-benzopyran-2-ones (3a-d) with chloroacetyl chloride and thioglycolic acid affords the corresponding four-membered azetidinones (4a-d) and five-membered thiazolidinones (5a-d) respectively. All the compounds were tested for their acute toxicity, effects on gross behaviour, spontaneous motor activity (SMA), anorexigenic activity, neuroleptic activity and anticonvulsant activity. Compounds 4a and 5d exhibited C.N.S. depressant activity.

Synthesis of 3-(&α-Arylazo-benzylideneamino/furfurylideneamino)coumarins and Their Anti-inflammatory Activity

3-(α-Arylazo-benzylideneamino/furfurylideneamino)coumarins (IVa-k) have been prepared by the coupling reaction of 3-arylidene-aminocoumarins (IIIa-c) with arenediazonium chlorides.The coumarins III in turn have been obtained by condensation of appropriate aldehydes with 3-aminocoumarin (II).An improved synthesis of 3-aminocoumarin (II) is also described.