147332-01-2

Upstream product

• 129083-21-2 (E)-4-methyl-1-(phenylsulfonyl)pent-1-en-3-ol 
• 147235-42-5 ((E)-3-Methoxymethoxy-4-methyl-pent-1-ene-1-sulfonyl)-benzene 
• 133886-24-5 ((E)-1-Benzenesulfonyl-3-methoxymethoxy-4-methyl-pent-1-enyl)-trimethyl-silane 
• 1026318-55-7 ((2R,3S)-1-Benzenesulfonyl-3-methoxymethoxy-2,4-dimethyl-pentyl)-trimethyl-silane 
• 71398-23-7 (+)-(S)-4-Methylphenylsulfinyl phenyl sulfone 
• 132016-59-2 (S)-(E)-4-methyl-1-(phenylsulfonyl)-1-penten-3-ol 
• 147235-42-5 ((E)-(S)-3-Methoxymethoxy-4-methyl-pent-1-ene-1-sulfonyl)-benzene 

Downstream Products

• 147332-03-4 (1E,3R,4S,5S)-5-(methoxymethoxy)-4,6-dimethyl-1-(phenylsulfonyl)-1-hepten-3-ol 
• 147235-51-6 (1E,3R,4S,5S)-5-(methoxymethoxy)-4,6-dimethyl-1-(trimethylsilyl)-1-(phenylsulfonyl)-1-hepten-3-ol 
• 147235-49-2 (E)-(4R,5S)-1-Benzenesulfonyl-5-methoxymethoxy-4,6-dimethyl-hept-1-en-3-one 
• 147235-50-5 (1E,4R,5S)-5-hydroxy-4,6-dimethyl-1-(phenylsulfonyl)-1-hepten-3-one 

Relevant academic research and scientific papers

Synthesis and conjugate additions to (E)-γ-alkoxy-α-substituted-α,β-unsaturated sulfones

(E)-γ-hydroxy-α,β-unsaturated sulfones have been readily functionalized at α-position via protection of hydroxyl group, metalation with n-BuLi and subsequent reaction with electrophiles. The conjugate addition of organolithiums to (E)-γ-methoxymethoxy-α-trimethylsilyl-α,β-unsaturated phenyl sulfones in Et2O is highly syn-stereoselective