147369-12-8

Upstream product

• 197891-66-0 4-benzyloxycarbamate-butyraldehyde diethyl acetal 
• 147369-09-3 7,7-Dichloro-6-oxo-2-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 
• 95656-88-5 benzyl 3-hydroxypyrrolidine-1-carboxylate 
• 501-53-1 benzyl chloroformate 
• 68471-57-8 2,3-dihydro-pyrrole-1-carboxylic acid benzyl ester 

Downstream Products

• 95456-65-8 (3aR,6aR)-2-Oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester 
• 95456-65-8 (1R,5R)-(-)-6-aza-6-benzyloxycarbonyl-2-oxabicyclo[3.3.0]octan-3-one 
• 136599-33-2 (1S,5S)-(+)-6-aza-6-benzyloxycarbonyl-2-oxabicyclo[3.3.0]octan-3-one 

Relevant academic research and scientific papers

Microbial Baeyer-Villiger oxidation applied to the synthesis of the N-protected (1R,5R)-Geisman-Waiss lactone

Using whole cell Baeyer-Villiger biooxidation as a key step and depending on the choice of the biocatalyst {E. coli TOP10[pQR239] or Acinetobacter TD63}, the synthesis of nearly enantiopure N-protected (1R,5R)-(-)-Geisman-Waiss lactone (92% ee) or its (1R

Cycloaddition Reaction of Cyclic Enecarbamates and Enamides With Ketenes. A Short and Efficient Synthesis of the Geissman-Waiss Lactone.

The synthesis of several 2-aza-bicycloheptan-6-ones has been achieved in a regiospecific manner through a cycloaddition reaction between five-membered cyclic enecarbamates and enamides and free ketenes.The synthetic potential of this new meth