147397-85-1

Basic information

• Product Name: 1-methyl-2-hydroxy-3-phenylselenenylcyclohexan-1-acetic acid lactone
• CAS NO: 147397-85-1
• Molecular Weight: 309.267
• Mol File: 147397-85-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-hydroxy-3-phenylselenenylcyclohexan-1-acetic acid lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-hydroxy-3-phenylselenenylcyclohexan-1-acetic acid lactone(147397-85-1)
• EPA Substance Registry System: 1-methyl-2-hydroxy-3-phenylselenenylcyclohexan-1-acetic acid lactone(147397-85-1)

Safety Data

• Hazardous Substances Data: 147397-85-1(Hazardous Substances Data)

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 105105-56-4 2-(1-methylcyclohex-2-en-1-yl)acetic acid 
• 21378-21-2 3-methylcyclohex-2-en-1-ol 
• 71593-69-6 1-methyl-2-cyclohexen-1-acetic acid ethyl ester 

Relevant articles and documents

The claisen rearrangement in synthesis: Acceleration of the johnson orthoester protocol en route to bicyclic lactones

Catalysis of the Claisen orthoester rearrangement of triethyl orthoacetate and a number of 2-cycloalken-1-ols has been achieved using acidic catalysis and brief microwave thermolysis in DMF. Unlike conventional methods of thermolysis, very high yields of rearranged products are typically obtained in less than ten minutes, and the Claisen products themselves require no further purification. The synthetic utility of the products so obtained is demonstrated in a general synthesis of functionalized bicyclic lactones.