147397-88-4Relevant academic research and scientific papers
Biotransformations of bicyclic trimethylcyclohexane chloro-, bromo-and iodolactones using fungal strains
Grabarczyk, Malgorzata,Bialoska, Agata
, p. 408 - 414 (2010)
Several fungal strains (Fusarium, Botrytis, Beauveria) were screened for their ability to transform three bicyclic halo-γ-lactones with a trimethylcyclohexane ring. Most of the micro-organisms carried out hydrolytic dehalogenation and transformed these la
Lactones 18. Synthesis of bicyclic lactones with methyl-, di- and trimethyl substituted cyclohexane system
Grabarczyk,Szumny,Gladkowski,Bialonska,Ciunik,Wawrzenczyk
, p. 1763 - 1771 (2007/10/03)
Starting from racemic γ,δ-unsaturated esters (1a-d) twelve bicyclic γ-lactones with the cyclohexane system substituted with various number of methyl groups were synthesized. The esters mentioned were subjected to the alkaline hydrolysis and then to iodola
Inversion of the direction of stereoinduction in the coupling of chiral γ,δ-unsaturated fischer carbene complexes with o-ethynylbenzaldehyde
Ghorai, Binay K.,Menon, Suneetha,Lee Johnson, Dennis,Herndon, James W.
, p. 2121 - 2124 (2007/10/03)
(matrix presented) A variety of γ,δ-unsaturated carbene complexes that feature a stereogenic center at the β-carbon couple with 2-ethynylbenzaldehyde to afford hydrophenanthrene derivatives with a high degree of stereoinduction. The direction of stereoinduction is opposite for examples where the stereogenic center is acyclic vs examples where it is within a ring.
The claisen rearrangement in synthesis: Acceleration of the johnson orthoester protocol en route to bicyclic lactones
Jones, Graham B.,Huber, Robert S.,Chau, Sotheary
, p. 369 - 380 (2007/10/02)
Catalysis of the Claisen orthoester rearrangement of triethyl orthoacetate and a number of 2-cycloalken-1-ols has been achieved using acidic catalysis and brief microwave thermolysis in DMF. Unlike conventional methods of thermolysis, very high yields of rearranged products are typically obtained in less than ten minutes, and the Claisen products themselves require no further purification. The synthetic utility of the products so obtained is demonstrated in a general synthesis of functionalized bicyclic lactones.
