147402-72-0Relevant academic research and scientific papers
Hydroboration-azide alkylation as efficient tandem reactions for the synthesis of chiral non racemic substituted pyrrolidines
Salmon, Anne,Carboni, Bertrand
, p. 31 - 37 (2007/10/03)
The synthesis of chiral non racemic substituted pyrrolidines from homoallylic alcohols is presented. These precursors are readily converted via the azides to the corresponding pyrrolidines using hydroboration-cycloalkylation tandem reactions as key steps.
Ligands for brain cholinergic channel receptors: Synthesis and in vitro characterization of novel isoxazoles and isothiazoles as bioisosteric replacements for the pyridine ring in nicotine
Garvey,Wasicak,Elliott,Lebold,Hettinger,Carrera,Lin,He,Holladay,Anderson,Cadman,Raszkiewicz,Sullivan,Arneric
, p. 4455 - 4463 (2007/10/02)
Ligands which activate neuronal nicotinic acetylcholine receptors (nAChRs) represent a potential approach for the palliative treatment for the symptoms of memory loss associated with Alzheimer's disease (AD). Based upon this approach, a series of novel 3,
