147404-72-6Relevant articles and documents
N-ARYLYLMETHYLINDAZOLE MODULATORS OF PPARG
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, (2013/06/06)
The invention provides molecular entities that bind with high affinity to PPARG (PPARy), inhibit cdJk5-mediated phosphorylation of PP ARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes or obesity. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.
Cyclic compounds and their use
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, (2008/06/13)
The present invention relates to a compounds represented by the following formula or salts thereof. STR1 The above compounds have strong angiotensin II antagonistic action, antihypertensive action and action on central nervous system, which are useful for
COMPOUND WHICH IS ANGIOTENSIN II ANTAGONIST
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, (2008/06/13)
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