147404-72-6

Usage

Uses

Used in Pharmaceutical Industry:
4'-(Bromomethyl)biphenyl-2-carboxamide is used as an intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting the angiotensin II receptor. It plays a crucial role in the development of drugs like Telmisartan, which is an angiotensin II receptor antagonist used to treat hypertension and cardiovascular diseases.
Used in Chemical Synthesis:
In the chemical industry, 4'-(Bromomethyl)biphenyl-2-carboxamide serves as a building block for the creation of more complex organic molecules. Its bromomethyl group can be used in various organic reactions, such as nucleophilic substitution, to introduce different functional groups into the molecule, leading to a wide range of potential applications in the synthesis of specialty chemicals and materials.
Used in Research and Development:
4'-(Bromomethyl)biphenyl-2-carboxamide is also utilized in research and development settings, where it can be employed as a starting material for the exploration of new chemical reactions and the synthesis of novel compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 39627-24-2 4'-Methyl[1,1'-biphenyl]-2-carboxamide 
• 4001-73-4 2-Bromobenzamide 
• 5720-05-8 4-methylphenylboronic acid 

Relevant academic research and scientific papers

N-ARYLYLMETHYLINDAZOLE MODULATORS OF PPARG

The invention provides molecular entities that bind with high affinity to PPARG (PPARy), inhibit cdJk5-mediated phosphorylation of PP ARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes or obesity. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.

Heterocyclic compounds having angiotensin II antagonistic activity and use thereof

This invention relates to a compound represented by the formula STR1 wherein the ring A stands for a 5-10 membered aromatic heterocyclic group optionally having, besides R1 and R2, further substituents; R1 stands for an op

Cyclic compounds and their use

The present invention relates to a compounds represented by the following formula or salts thereof. STR1 The above compounds have strong angiotensin II antagonistic action, antihypertensive action and action on central nervous system, which are useful for

Process for producing 4-bromomethylbiphenyl compounds

A process for the production of a compound of general formula STR1 wherein R represents cyano, carboxy which may be esterified or amidated or tetrazolyl which may be substituted, comprising brominating the corresponding methyl compound with a brominating agent such as N -bromoacetamide, N-bromophtalimide, N-bromosuccinimide and so on in a halogenated hydrocarbon solvent in the presence of an azobis compound.