147406-85-7Relevant academic research and scientific papers
TANDEM GENERATION AND INTRAMOLECULAR TRAPPING OF CHIRAL STABILISED AZOMETHINE YLIDS WITH ALKYNE DIPOLAROPHILES
Harwood, Laurence M.,Kitchen, Lara C.
, p. 6603 - 6606 (2007/10/02)
Due to steric contraints imposed upon the bridging chain by the three-carbon linear unit associated with the alkyne, hex-5-ynal condenses with (5R)-phenylmorpholin-2-one (1) and undergoes intramolecular 3+2 dipolar cycloaddition via the syn-azomethine yli
Enantiocontrolled construction of bicyclic proline derivatives via one-pot generation and intramolecular trapping of chiral stabilised azomethine ylids
Harwood,Lilley
, p. 537 - 540 (2007/10/02)
Aldehydes possessing unsaturation at C-5 or C-6 condense with nylmorpholin-2-one (1), generating chiral stabilised azomethine ylids which undergo concommitant diastereospecific intramolecular 3+2 dipolar cycloaddition to furnish adducts (2), (4), and (5)
