147437-40-9

Upstream product

• 147437-39-6 Benzyl 2,3,6-Trideoxy-3-C-carboxyl-6-C-propyl-D-galactofuranoside γ-Lactone 
• 110-62-3 pentanal 
• 4412-91-3 furan-3-methanol 
• 131719-75-0 (2R,6R)-2-Butyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-6-(1-ethoxy-ethoxy)-6H-pyran-3-one 
• 131719-77-2 (2R,3R,4R,6R)-2-Butyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-6-(1-ethoxy-ethoxy)-tetrahydro-pyran-3-ol 
• 131719-79-4 (2R,3R,4S,6R)-2-Butyl-3,6-bis-(1-ethoxy-ethoxy)-tetrahydro-pyran-4-carboxylic acid 
• 147437-37-4 tert-Butyl-[(2R,3R,4R,6R)-2-butyl-3,6-bis-(1-ethoxy-ethoxy)-tetrahydro-pyran-4-ylmethoxy]-dimethyl-silane 
• 131719-76-1 (2R,4R,6R)-2-Butyl-4-(tert-butyl-dimethyl-silanyloxymethyl)-6-(1-ethoxy-ethoxy)-dihydro-pyran-3-one 
• 147437-38-5 (2R,3R,4S,6R)-2-Butyl-3,6-bis-(1-ethoxy-ethoxy)-tetrahydro-pyran-4-carbaldehyde 
• 131719-78-3 [(2R,3R,4R,6R)-2-Butyl-3,6-bis-(1-ethoxy-ethoxy)-tetrahydro-pyran-4-yl]-methanol 
• 147437-28-3 (2R)-2-Butyl-4-(tert-butyldimethylsilyloxymethyl)-6-hydroxy-6H-pyran-3(2H)-one 
• 131830-44-9 (1R)-1-<2-(3-tert-Butyldimethylsilyloxymethylfuryl)>-1-pentanol 
• 131719-80-7 2,3,6-Trideoxy-3-C-carboxyl-6-C-propyl-D-galactofuranose γ-Lactone 
• 131719-82-9 1-<2-(3-Hydroxymethylfuryl)>-1-pentanol 

Downstream Products

• 131719-81-8 (3aS,6R,6aR)-2-Benzyloxy-6-butyl-4-(1-ethoxy-ethoxy)-hexahydro-furo[3,4-b]furan 

Relevant academic research and scientific papers

Enantioselective synthesis of (-)-canadensolide

Chiral synthesis of canadensolide has been achieved by using the Sharpless kinetic resolution of the 2-furylcarbinol derivative(11), followed by its oxidative conversion into the corresponding pyranone(12) as key reactions.

Enantioselective synthesis of bislactone structure: A formal synthesis of (-)-canadensolide

An enantioselective synthesis of the canadensolide-type bislactone via the versatile pyranone derived from the chiral furylcarbinol (R)-3 has been accomplished. A formal synthesis of (-)-canadensolide is also described.