14744-30-0Relevant academic research and scientific papers
Dimethyl (2-Furyl)-N-(2-Methoxyphenyl)Aminomethylphosphonate Induces Apoptosis in Esophageal Squamous Cancer Cells. Structure Versus Activity of its Selected Analogs
Klimczak, Anna Agnieszka,Matusiak, Agnieszka,Lewkowski, Jaroslaw,Bitner, Jan,Szemraj, Janusz,Kontek, Renata
, p. 1088 - 1099 (2015/08/04)
Cytotoxicities of several new aminophosphonic compounds bearing 2-furyl moiety 2b-d and 3a-c on KYSE 30, 150, and 270 esophageal cancer cell lines are reported here. The qualitative study on correlations between the structure and cytotoxic activity of fur
Synthesis of new N-arylamino(2-furyl)methylphosphonic acid diesters, and in vitro evaluation of their cytotoxicity against esophageal cancer cells
Klimczak, Anna Agnieszka,Kuropatwa, Agnieszka,Lewkowski, Jaroslaw,Szemraj, Janusz
, p. 852 - 860 (2013/04/23)
N-Furfurylideneanilines and N-arylamino(2-furyl)methylphosphonates with tolyl and anisyl moieties were synthesized by the addition of phosphites to azomethine bond of corresponding Schiff bases and their NMR spectroscopic properties were investigated. The
Development of strong Bronsted base catalysis: Catalytic direct-type Mannich reactions of non-activated esters via a product-base mechanism
Yamashita, Yasuhiro,Suzuki, Hirotsugu,Kobayashi, Shu
supporting information; body text, p. 5750 - 5752 (2012/08/28)
A catalytic Mannich reaction of a simple ester with no activating functionality at the α-position via a product-base mechanism was reported. The desired Mannich adducts were obtained in high yields using a catalytic amount of KH. This is a rare example of
Anti-selective, catalytic asymmetric vinylogous mukaiyama mannich reactions of pyrrole-based silyl dienolates with N-aryl aldimines
Curti, Claudio,Battistini, Lucia,Ranieri, Beatrice,Pelosi, Giorgio,Rassu, Gloria,Casiraghi, Giovanni,Zanardi, Franca
supporting information; experimental part, p. 2248 - 2252 (2011/05/19)
Pyrrole-based silyl dienolates undergo asymmetric vinylogous Mukaiyama Mannich reactions with a series of N-aryl aldimines in the presence of the Hoveyda-Snapper amino acid-derived silver(I) catalysts. The Mannich products-α,β-unsaturated δ-amino-γ-butyro
Synthesis of 2-arylbenzoxazoles from flash vacuum pyrolysis of 2-methoxy-N-(arenylidene)anilines
Chou, Chin-Hsing,Hsueh, Yu-Tan,Wang, Bo-Chi
experimental part, p. 301 - 305 (2011/10/18)
Flash vacuum pyrolysis of 2-methoxy-N-(arenylidene)anilines 2a-g at 700 °C and 1 × 10-2 Torr gave the corresponding 2-arylbenzoxazoles 1a-g.
Dimethylzinc-mediated, enantioselective synthesis of propargylic amines
Zani, Lorenzo,Eichhorn, Torsten,Bolm, Carsten
, p. 2587 - 2600 (2008/04/01)
A one-pot, enantioselective synthesis of N-aryl propargylic amines, using alkynylation reagents obtained from dimethylzinc and terminal acetylenes in combination with various aldehydes and o-methoxyaniline as starting materials, has been developed. Enanti
An efficient synthesis of isoindolo[2,1-a]quinoline derivatives via imino Diels-Alder and intramolecular Diels-Alder reactions with furan
Kouznetsov, Vladimir V.,Cruz, Uriel Mora,Zubkov, Fedor I.,Nikitina, Eugenia V.
, p. 375 - 384 (2008/01/06)
The straightforward synthesis of new isoindolo[2,1-a]quinoline derivatives from 2,4-disubstituted 1,2,3,4-tetrahydroquinolines bearing a furan fragment via the intramolecular Diels-Alder reaction is reported. The synthesis of key precursors was realized w
Synthesis of imines, diimines and macrocyclic diimines as possible ligands, in aqueous solution
Simion, Alina,Simion, Cristian,Kanda, Tadeshige,Nagashima, Satoko,Mitoma, Yoshiharu,Yamada, Tomoko,Mimura, Keisuke,Tashiro, Masashi
, p. 2071 - 2078 (2007/10/03)
Although it is recognized that the presence of water is disadvantageous for imine synthesis, we demonstrate that such synthesis can be effective in completely aqueous media, without any catalyst and under mild conditions. Thus, arylaryl, aryl-alkyl, alkyl-aryl and alkyl-alkyl monoimines as well as a large variety of diimines are obtained by direct condensation of the corresponding carbonyl compounds and amines, in water. The same process is used to synthesize macrocyclic diimines starting from methylene, ethylene, trimethylene and tetramethylene glycol bis(2-formylphenyl ether) and ethylene-, trimethylene- and tetramethylene-diamine, some of these macrocycles being known for their chelating properties.
Furfurylidene Arylamine Complexes of Dioxouranium(VI) Chloride and Thiocyanate
Panda, C. R.,Nayak, S. C.,Chakravortty, V.,Dash, K. C.
, p. 141 - 143 (2007/10/02)
Dioxouranium(VI) chloride and thiocyanate form diamagnetic, non-electrolytic complexes of the type , where SB denotes bidentate schiff bases prepared by in situ reaction of 2-furan carboxaldehyde with equivalent amounts of different aromatic a
Studies on the Electronic Absorption Spectra of Some Selected Furan Derivatives. Molecular Orbital Calculations
Abu-Eittah, Rafie Hassan,Hammed, Maher Mohamed
, p. 844 - 851 (2007/10/02)
The electronic absorption spectra of three groups of furan derivatives: 2-formyl, 2-acetylfuran, and 2-furoic acid, N-(2-furylmethylene)amines and phenylfurans were investigated.The predominant conformation as well as the polarity of the molecule could be predicted from its spectrum.The investigated molecules were proved to be " all planar" configuration which led to substantial interaction between the electronic states of the subsystems.The preferred conformations of N-(2-furylmethylene)methylamine and N-(2-furylmethylene)aniline were predicted with the aid of molecular orbital calculations.
