147495-99-6

Basic information

• Product Name: VZ 564
• Synonyms: VZ 564
• CAS NO: 147495-99-6
• Molecular Formula: C13H16N2O3
• Molecular Weight: 248.27774
• Mol File: 147495-99-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 447°Cat760mmHg
• Flash Point: 224.1°C
• Appearance: /
• Density: 1.275g/cm³
• Vapor Pressure: 8.98E-09mmHg at 25°C
• Refractive Index: 1.609
• PKA: 10.26±0.50(Predicted)
• CAS DataBase Reference: VZ 564(CAS DataBase Reference)
• NIST Chemistry Reference: VZ 564(147495-99-6)
• EPA Substance Registry System: VZ 564(147495-99-6)

Safety Data

• Hazardous Substances Data: 147495-99-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H16N2O3/c1-18-12-5-4-10-6-9(2-3-11(10)7-12)8-15(17)13(14)16/h4-7,17H,2-3,8H2,1H3,(H2,14,16)

Relevant articles and documents

SUBSTITUTED 3,4-DIHYDRONAPHTHALENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PREPARATION PROCESSES

Substituted 3,4-dihydronaphthalenes of the formula I wherein R1 is a methyl or an amino group, R2 represents a hydrogen atom or a methyl group, and R3 is a linear or branched chain alkyl residue having 1 to 4 carbon atoms, an allyl or a crotyl group or a cyclopentyl group are disclosed which specifically inhibit 5-lipoxygenase and are useful in pharmaceutical compositions for prophylaxis and treatment of disorders attributable to the action of leucotrienes. The dihydronaphthalenes may be prepared by reacting a compound of formula II. with hydroxylamine or a salt thereof to form the corresponding oxime, reducing the oxime to a hydroxylamine of formula III and introducing a -CO-R1 group.