147497-64-1

Basic information

• Product Name: Davasaicin
• Synonyms: Davasaicin
• CAS NO: 147497-64-1
• Molecular Formula: C₂₂H₃₀N₂O₃
• Molecular Weight: 370.49
• Mol File: 147497-64-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 594.6°Cat760mmHg
• Flash Point: 313.4°C
• Appearance: /
• Density: 1.092g/cm³
• Vapor Pressure: 4.16E-14mmHg at 25°C
• Refractive Index: 1.555
• PKA: 15.63±0.46(Predicted)
• CAS DataBase Reference: Davasaicin(CAS DataBase Reference)
• NIST Chemistry Reference: Davasaicin(147497-64-1)
• EPA Substance Registry System: Davasaicin(147497-64-1)

Safety Data

• Hazardous Substances Data: 147497-64-1(Hazardous Substances Data)

Usage

Uses

Davasaicin is a capsaicin analog used as a potent anti-inflammatory analgesic.

InChI:InChI=1/C22H30N2O3/c1-16-6-7-18(13-17(16)2)5-4-11-24-22(25)15-19-8-9-20(27-12-10-23)21(14-19)26-3/h6-9,13-14H,4-5,10-12,15,23H2,1-3H3,(H,24,25)

Upstream product

• 174661-97-3 Davasaicin 
• 860782-00-9 2-[4-(cyanomethoxy)-3-methoxyphenyl]-N-[(3,4-dimethylphenyl)propyl]acetamide 

Downstream Products

• 174661-97-3 Davasaicin 
• 180304-22-7 N-{3-(3,4-dimethylphenyl)propyl}-4-{2-(N-benzyloxycarbonyl)-aminoethoxy}-3-methoxyphenylacetamide 
• 180304-25-0 N-{3-(3,4-dimethylphenyl)propyl}-4-{2-(N-ethyloxycarbonyl)aminoethoxy}-3-methoxy phenylacetamide 

Relevant articles and documents

CATALYTIC HYDROGENATION OF NITRILES TO PRODUCE CAPSAICINOID DERIVATIVES AND AMINE COMPOUNDS, AND METHODS FOR PURIFIYING AND OBTAINING THE POLYMORPHS THEREOF

Processes for preparing an amine compound by catalytically hydrogenating a precursor nitrile compound. In a particular aspect, the present hydrogenation process occurs in a dipolar organic solvent in the presence of a palladium/carbon catalyst and a strong anhydrous protic acid. In a further aspect, the preferred embodiment relates to a process for deprotecting a compound to produce an amine compound. In yet a further aspect, the preferred embodiment relates to amine products produced by the present processes. These amine products may be used for a variety of purposes.

N-arylalkylphenylacetamide derivatives

N-arylalkylphenylacetamide compounds of formula (I), and pharmaceutically acceptable salts thereof, possess potent analgesic and anti-inflammatory activities.

Novel phenylacetamide derivatives and processes for the preparation thereof

The present invention provides novel phenylacetamide derivatives having the following formula wherein:, X is a hydrogen, halogen, hydroxy, nitro, amino, R1, NR1R2, NHR1 or OR1 wherein R1 and R2 are an optionally substituted C1 8 alky