147539-21-7

Basic information

• Product Name: 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE
• Synonyms: 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE;N-(1-Methylethyl)-2-(1-Piperazinyl)-3-Pyridinamine;ISOPROPYL[2-(PIPERAZIN-1-YL)-3-PYRIDYL]AMINE;3-PYRIDINAMINE,N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-;dihydrochloride,monohydrate;N-Isopropyl[2-(piperazin-1-yl)-3-pyridyl]amine;3-Pyridinamine, N-(1-methylethyl)-2-(1-piperazinyl-), dihydrochloride,monohydrate
• CAS NO: 147539-21-7
• Molecular Formula: C₁₂H₂₀N₄
• Molecular Weight: 220.314
• Mol File: 147539-21-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 392.0±37.0 °C(Predicted)
• Appearance: /
• Density: 1.080±0.06 g/cm3(Predicted)
• PKA: 9.17±0.30(Predicted)
• CAS DataBase Reference: 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE(147539-21-7)
• EPA Substance Registry System: 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE(147539-21-7)

Safety Data

• Hazardous Substances Data: 147539-21-7(Hazardous Substances Data)

Usage

General Description

3-Pyridylamine, N-(1-methylethyl)-2-(1-piperazinyl)-, dihydrochloride monohydrate is a chemical compound that is typically used in pharmaceutical research and development. It is a dihydrochloride monohydrate salt form of a compound that contains a pyridine ring, an isopropyl group, and a piperazine ring. 3-PYRIDYLAMINE, N-(1-METHYLETHYL)-2-(1-PIPERAZINYL)-,DIHYDROCHLORIDE MONOHYDRATE has potential applications in various therapeutic areas such as central nervous system disorders, inflammation, and oncology. It may also exhibit properties such as being an anti-inflammatory, analgesic, or antipsychotic agent. The compound's structural and chemical properties make it a potentially valuable candidate for further investigation in drug discovery and development processes.

InChI:InChI=1/C12H20N4.2ClH.H2O/c1-10(2)15-11-4-3-5-14-12(11)16-8-6-13-7-9-16;;;/h3-5,10,13,15H,6-9H2,1-2H3;2*1H;1H2

Upstream product

• 5470-18-8 2-Chloro-3-nitropyridine 
• 153473-24-6 1-tert-butoxycarbonyl-4-(3-nitro-2-pyridyl)piperazine 
• 111669-25-1 1-[1,1-dimethylethoxycarbonyl]-4-[3-amino-2-pyridinyl]piperazine 
• 87394-48-7 1-(3-nitro-2-pyridinyl)piperazine 
• 110-85-0 piperazine 
• 136818-14-9 1-[1,1-Dimethylethoxycarbonyl]-4-[3-(1-methylethylamino)-2-pyridinyl]piperazine 

Downstream Products

• 147920-10-3 (6-Benzyloxy-1H-indol-2-yl)-[4-(3-isopropylamino-pyridin-2-yl)-piperazin-1-yl]-methanone 
• 136817-66-8 1-[(6-Formyl-2-indolyl)carbonyl]-4-[3-(isopropylamino)-2-pyridinyl]piperazine 
• 136817-59-9 delavirdine 
• 136817-55-5 delavirdine 
• 1316754-35-4 2-(4-((1-benzyl-2-[⁽¹⁴⁾C]-imidazol-5-yl)methyl)piperazin-1-yl)-N-isopropylpyridin-3-amine 
• 1316754-33-2 1-(1-benzyl-2-[⁽¹⁴⁾C]-5-imidazoyl)-4-[3-(isopropylamino)-2-pyridyl]piperazine 
• 1316754-32-1 2-(4-((1-benzyl-2-(methylthio)-2-[⁽¹⁴⁾C]-imidazol-5-yl)methyl)-piperazin-1-yl)-N-isopropylpyridin-3-amine 
• 1316754-21-8 1-(1-benzyl-2-methylthio-2-[⁽¹⁴⁾C]-5-imidazoyl)-4-[3-(isopropylamino)-2-pyridyl]piperazine 
• 136817-51-1 1-[4-Methylindolyl-2-carbonyl]-4-[3-(1-methylethylamino)-2pyridinyl]piperazine 
• 136816-95-0 1-[5-Benzyloxyindolyl-2-carbonyl]-4-[3-(1-methylethyl)amino-2-pyridinyl]piperazine 
• 138863-11-3 1-[4-Methoxyindolyl-2-carbonyl]-4-[3-(1-methylethylamino)-2-pyridinyl]piperazine 
• 136816-84-7 1-<(5-fluoroindol-2-yl)carbonyl>-4-<3-<(methylethyl)amino>-2-pyridyl>piperazine 
• 403502-46-5 [5-(4-amino-phenyl)-1H-pyrrol-3-yl]-[4-(3-isopropylamino-pyridin-2-yl)-piperazin-1-yl]-methanone 
• 403502-41-0 [5-(2-amino-phenyl)-1H-pyrrol-2-yl]-[4-(3-isopropylamino-pyridin-2-yl)-piperazin-1-yl]-methanone 

Relevant articles and documents

Synthesis of 1-(1-benzyl-2-ethylthio-2-14C-5-imidazolyl)-4-{3- (1-isopropylamino)-2-pridyl} piperazine

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Strategy for 14C-labeling of a series of bis(heteroaryl) piperazines

Four bis(heteroaryl)piperazines labeled with carbon-14 in the 2-position of imidazole moiety were prepared as part of a 4-step (or 5-step) sequence from 5-hydroxymethyl-2-mercapto-1-benzylimida-zole-[2-14C] as a key synthetic intermediate which

Anti-aids piperazines

The present invention includes diaromatic substituted heterocyclic compounds (III) STR1 which are useful in treating individuals infected with the HIV virus. The invention includes certain previously generically disclosed anti-AIDS piperazinyl compounds (V) and a method of treating HIV infected individuals with the indoles of formula (V) and the anti-AIDS amines (X).