147539-80-8 Usage
General Description
5-Amino-2-indolecarboxylic acid methyl ester is a chemical compound with the molecular formula C10H10N2O2. It is an indole derivative and a methyl ester, commonly used in the synthesis of various pharmaceutical compounds. This chemical has been studied for its potential applications in the field of medicinal chemistry, particularly in the development of drugs targeting various biological processes. Its unique structure and properties make it a valuable building block in the synthesis of novel compounds with potential therapeutic applications. Additionally, it has been investigated for its potential role in the development of new materials for various industrial and scientific applications. Overall, 5-Amino-2-indolecarboxylic acid methyl ester is an important chemical compound with diverse potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 147539-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,5,3 and 9 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 147539-80:
(8*1)+(7*4)+(6*7)+(5*5)+(4*3)+(3*9)+(2*8)+(1*0)=158
158 % 10 = 8
So 147539-80-8 is a valid CAS Registry Number.
147539-80-8Relevant articles and documents
Structural influence of indole C5-N-substitutents on the cytotoxicity of seco-duocarmycin analogs
Choi, Taeyoung,Ma, Eunsook
, p. 357 - 367 (2011)
A series of racemic indole C5-substituted seco-cyclopropylindoline compounds (2,3 and 5-7) were prepared by coupling 1-(tert-butyloxycarbonyl)-3- (chlorocarbonyl)indoline (seg-A) with 5,6,7-trimethoxy-, 5,6-dimethoxy-, 5-amino-, 5-methylsulfonylamino- and 5-(N,N-dimethylaminosulfonylamino) indole-2-carboxylic acid as seg-B in the presence of 1-ethyl-3-(3- dimethylaminopropyl) carbodiimide. The synthetic compounds (2,3 and 5-7) were tested for cytotoxic activity against human cancer cell lines (COLO 205, SK-MEL-2, A549, and JEG-3) using the MTT assay.
