147580-31-2Relevant academic research and scientific papers
Pyrrolopyrazine derivatives
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, (2008/06/13)
The novel pyrrolopyrazines of the general formula STR1 wherein one of R1 and R2 signifies aryl and the other signifies hydrogen, lower alkyl or aryl or R1 and R2 together with the two carbon atoms denoted by α and β signify the group A; STR2 R3 signifies hydrogen or lower alkyl and R4 signifies hydrogen or R3 and R4 together signify an additional C/N bond; R5 signifies hydrogen or lower alkyl; R6 signifies hydrogen or lower alkyl; R7 signifies hydrogen, halogen, lower alkyl, optionally substituted lower alkoxy, or C3-6 -cycloalkyl, C4-6 -cycloalkenyl, C3-6 -cycloalkyloxy, hydroxy, trifluoro- methanesulphonyloxy or optionally substituted benzyl- oxycarbonyloxy; and the dotted line signifies an optional additional C/C bond, and pharmaceutically acceptable acid addition salts of the compounds of formula I can be used in the control or prevention of illnesses or in the improvement of health, especially in the control or prevention of depressive states, cognitive disorders and neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
