1476030-84-8Relevant academic research and scientific papers
Formation of dihydronaphthalenes via organocatalytic enatioselective michael-aldol cascade reactions with arylalkanes
Li, Xiangmin,Wang, Sinan,Li, Tengfei,Li, Jian,Li, Hao,Wang, Wei
supporting information, p. 5634 - 5637 (2013/12/04)
An organocatalytic highly enantioselective Michael-aldol cascade access to valuable chiral dihydronaphthalenes has been realized. Notably, the strategy via activation of nucleophilic alkyl chains by introducing nitro, chloro, or CF3 group(s) at the ortho- and/or para-position(s) on an aromatic ring renders them readily deprotonated to produce highly reactive nulecophilic species in the cascade process under mild conditions.
