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7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE, commonly known as brotizolam, is a benzodiazepine-class psychoactive drug that functions as a sedative-hypnotic agent. It is primarily used for its anxiolytic and sleep-inducing properties, working by potentiating the effects of gamma-aminobutyric acid (GABA) in the brain, which results in sedation and muscle relaxation. Due to its potential for addiction and dependence, it is considered a controlled substance and should be administered under strict medical guidance.

147644-11-9

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147644-11-9 Usage

Uses

Used in Pharmaceutical Industry:
7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE is used as a sedative-hypnotic for the short-term treatment of severe insomnia. It is prescribed to help patients achieve restful sleep by enhancing the inhibitory effects of GABA, thus promoting relaxation and reducing the time taken to fall asleep.
Used in Psychiatry:
7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE is used as an anxiolytic to manage anxiety disorders. It helps alleviate symptoms of anxiety by modulating the GABAergic system, providing a calming effect and reducing feelings of tension and worry.
Used in Sleep Medicine:
7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE is used as a sleep aid for individuals suffering from sleep disturbances. It is particularly beneficial for those with difficulty initiating or maintaining sleep, as it facilitates the onset of sleep and improves sleep quality.
Used in Controlled Substances Regulation:
Due to its potential for addiction and dependence, 7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE is used under strict medical supervision and is regulated as a controlled substance. This ensures that its prescription and use are monitored to prevent misuse and ensure patient safety.

Check Digit Verification of cas no

The CAS Registry Mumber 147644-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,6,4 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 147644-11:
(8*1)+(7*4)+(6*7)+(5*6)+(4*4)+(3*4)+(2*1)+(1*1)=139
139 % 10 = 9
So 147644-11-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H9BrO2/c10-7-2-3-8-9(6-7)12-5-1-4-11-8/h2-3,6H,1,4-5H2

147644-11-9 Well-known Company Product Price

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  • Alfa Aesar

  • (H27594)  7-Bromo-3,4-dihydro-1,5-benzodioxepin, 96%   

  • 147644-11-9

  • 1g

  • 482.0CNY

  • Detail
  • Alfa Aesar

  • (H27594)  7-Bromo-3,4-dihydro-1,5-benzodioxepin, 96%   

  • 147644-11-9

  • 5g

  • 1475.0CNY

  • Detail
  • Alfa Aesar

  • (H27594)  7-Bromo-3,4-dihydro-1,5-benzodioxepin, 96%   

  • 147644-11-9

  • 25g

  • 4554.0CNY

  • Detail

147644-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-BROMO-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE

1.2 Other means of identification

Product number -
Other names 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]dioxepine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147644-11-9 SDS

147644-11-9Relevant academic research and scientific papers

Anilide derivative, production and use thereof

-

, (2008/06/13)

This invention is to provide a compound of the formula: wherein R1is an optionally substituted 5- to 6-membered ring; the ring A is an optionally substituted 6- to 7-membered ring; the ring B is an optionally substituted benzene ring; n is an integer of 1 or 2; Z is a chemical bond or a divalent group; R2is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, (2) an optionally substituted nitrogen-containing heterocyclic ring group which may contain a sulfur atom or an oxygen atom as ring constituting atoms and wherein a nitrogen atom may form a quaternary ammonium, (3) a group binding through a sulfur atom or (4) a group of the formula: ?wherein k is 0 or 1, and when k is 0, a phosphorus atom may form a phosphonium; and R5and R6are independently an optionally substituted hydrocarbon group, an optionally substituted hydroxy group or an optionally substituted amino group, and R5and R6may bind to each other to form a cyclic group together with the adjacent phosphorus atom, or a salt thereof , which is useful for antagonizing CCR5 and also for the prevention and treatment of infectious disease of HIV.

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