147664-63-9 Usage
General Description
Pexiganan is a synthetic analog of the antimicrobial peptide magainin, which is an 11-amino acid peptide and is being developed as a topical treatment for diabetic foot ulcers and other skin infections. It is a selective, cationic antimicrobial peptide that disrupts bacterial membranes, leading to rapid cell lysis and killing of a broad spectrum of bacteria, including both gram-positive and gram-negative species. Pexiganan has also shown promising activity against biofilm-forming bacteria, which are often resistant to traditional antibiotics. Overall, pexiganan has the potential to be an effective and innovative treatment for various types of skin infections, particularly in the context of diabetic foot ulcers where traditional antibiotics may be less effective due to impaired blood flow and tissue viability in the affected area.
Check Digit Verification of cas no
The CAS Registry Mumber 147664-63-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,6,6 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 147664-63:
(8*1)+(7*4)+(6*7)+(5*6)+(4*6)+(3*4)+(2*6)+(1*3)=159
159 % 10 = 9
So 147664-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C122H210N32O22/c1-13-77(9)102(152-98(155)71-132)120(174)135-73-100(157)139-86(50-26-35-59-125)110(164)150-96(69-82-44-20-16-21-45-82)118(172)148-93(66-74(3)4)116(170)145-90(54-30-39-63-129)113(167)142-87(51-27-36-60-126)109(163)137-79(11)105(159)141-88(52-28-37-61-127)112(166)143-91(55-31-40-64-130)114(168)149-95(68-81-42-18-15-19-43-81)107(161)134-72-99(156)138-85(49-25-34-58-124)108(162)136-80(12)106(160)147-97(70-83-46-22-17-23-47-83)119(173)153-101(76(7)8)121(175)146-92(56-32-41-65-131)115(169)154-103(78(10)14-2)122(176)151-94(67-75(5)6)117(171)144-89(53-29-38-62-128)111(165)140-84(104(133)158)48-24-33-57-123/h15-23,42-47,74-80,84-97,101-103H,13-14,24-41,48-73,123-132H2,1-12H3,(H2,133,158)(H,134,161)(H,135,174)(H,136,162)(H,137,163)(H,138,156)(H,139,157)(H,140,165)(H,141,159)(H,142,167)(H,143,166)(H,144,171)(H,145,170)(H,146,175)(H,147,160)(H,148,172)(H,149,168)(H,150,164)(H,151,176)(H,152,155)(H,153,173)(H,154,169)/t77-,78-,79-,80-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,101-,102-
