Welcome to LookChem.com Sign In|Join Free

CAS

  • or

14770-88-8

Post Buying Request

14770-88-8 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

14770-88-8 Usage

Description

(E)-3-(5-methylthiophen-2-yl)acrylic acid is a chemical compound with the molecular formula C8H8O2S. It is a carboxylic acid and contains a thiophene ring substituted with a methyl group. (E)-3-(5-methylthiophen-2-yl)acrylic acid has a trans geometry, indicated by the "(E)" prefix in its name. Thiophene-based compounds have diverse applications in pharmaceuticals, agrochemicals, and materials science, and (E)-3-(5-methylthiophen-2-yl)acrylic acid may be used as a building block in the synthesis of such compounds. Its properties and potential uses make it an interesting target for further study and development in various fields of chemistry and industry.

Uses

Used in Pharmaceutical Industry:
(E)-3-(5-methylthiophen-2-yl)acrylic acid is used as a building block for the synthesis of pharmaceutical compounds due to its unique structure and properties.
Used in Agrochemical Industry:
(E)-3-(5-methylthiophen-2-yl)acrylic acid is used as a building block for the synthesis of agrochemical compounds, potentially offering new solutions for pest control and crop protection.
Used in Materials Science:
(E)-3-(5-methylthiophen-2-yl)acrylic acid is used as a building block for the development of new materials with specific properties, such as conductivity, stability, or reactivity, for various applications in materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 14770-88-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,7 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14770-88:
(7*1)+(6*4)+(5*7)+(4*7)+(3*0)+(2*8)+(1*8)=118
118 % 10 = 8
So 14770-88-8 is a valid CAS Registry Number.

14770-88-8Relevant articles and documents

PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE

-

Page/Page column 19; 20, (2017/07/06)

The present invention deals with new flavivirus inhibitors, compositions comprising said inhibitors and methods for the treatment of disorders related to a viral infection, such as a disease due to a flavivirus infection, comprising administering said inhibitors.

A METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES

-

Paragraph 00176, (2015/02/25)

Provided herein are analogs of unnatural nucleotides bearing predominantly hydrophobic nucleobase analogs that form unnatural base pairs during DNA polymerase- mediated replication of DNA or RNA polymerase-mediated transcription of RNA. In this manner, the unnatural nucleobases can be introduced in a site-specific way into oligonucleotides (single or double stranded DNA or RNA), where they can provide for site-specific cleavage, or can provide a reactive linker than can undergo functionalization with a cargo -bearing reagent by means of reaction with a primary amino group or by means of click chemistry with an alkyne group of the unnatural nucleobase linker.

Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents

Leong, Sze Wei,Mohd Faudzi, Siti Munirah,Abas, Faridah,Mohd Aluwi, Mohd Fadhlizil Fasihi,Rullah, Kamal,Wai, Lam Kok,Abdul Bahari, Mohd Nazri,Ahmad, Syahida,Tham, Chau Ling,Shaari, Khozirah,Lajis, Nordin H.

, p. 16058 - 16081 (2015/01/08)

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88 and 97) exhibited greater or similar NO inhibitory activity in comparison with curcumin (14.7 ± 0.2 μM), notably compounds 88 and 97, which demonstrated the most significant NO suppression activity with IC50 values of 4.9 ± 0.3 μM and 9.6 ± 0.5 μM, respectively. A structure-activity relationship (SAR) study revealed that the presence of a hydroxyl group in both aromatic rings is critical for bioactivity of these molecules. With the exception of the polyphenolic derivatives, low electron density in ring-A and high electron density in ring-B are important for enhancing NO inhibition. Meanwhile, pharmacophore mapping showed that hydroxyl substituents at both meta- and para-positions of ring-B could be the marker for highly active diarylpentanoid derivatives.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 14770-88-8