147700-40-1Relevant articles and documents
Adenosine A(2A) antagonists with potent anti-cataleptic activity
Shimada, Junichi,Koike, Nobuaki,Nonaka, Hiromi,Shiozaki, Shizuo,Yanagawa, Koji,Kanda, Tomoyuki,Kobayashi, Hiroyuki,Ichimura, Michio,Nakamura, Joji,Kase, Hiroshi,Suzuki, Fumio
, p. 2349 - 2352 (2007/10/03)
Structure-activity relationships of 8-styrylxanthines for in vivo adenosine A(2A) antagonism were explored. Diethyl substitution both at the 1- and S-position was found to dramatically potentiate the anti-cataleptic activity.