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147739-88-6

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147739-88-6 Usage

Uses

6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine DiHCl

Check Digit Verification of cas no

The CAS Registry Mumber 147739-88-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,7,3 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 147739-88:
(8*1)+(7*4)+(6*7)+(5*7)+(4*3)+(3*9)+(2*8)+(1*8)=176
176 % 10 = 6
So 147739-88-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2.2ClH/c1-2-6-4-8-5-7(6)9-3-1;;/h1-3,8H,4-5H2;2*1H

147739-88-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7-Dihydro-5H-pyrrolo[3,4-b]pyridine

1.2 Other means of identification

Product number -
Other names 6,7-Dihydro-5H-pyrrolo3,4-bpyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147739-88-6 SDS

147739-88-6Relevant articles and documents

A robust process for an mGluR5 negative allosteric modulator: Difluoromethylation and sonogashira coupling on large scale

Sperry, Jeffrey B.,Farr, Roger M.,Levent, Mahmut,Ghosh, Mousumi,Hoagland, Steven M.,Varsolona, Richard J.,Sutherland, Karen

, p. 1854 - 1860 (2013/01/15)

The development of the potent and selective mGluR5 negative allosteric modulator (NAM) 1 is described. Key features in the process, which has been implemented on a multikilogram scale, include a high-temperature difluoromethylation reaction, a Sonogashira coupling, and careful control of residual Pd and Cu in the final API. Due to the relative nonpolar nature of the intermediates, water-miscible solvents were employed in all four steps to allow for direct crystallizations upon reaction completion. In addition, several crystalline morphologies of the API were discovered, and the isolation of the desired form II will be discussed.

CARBOXYAMINE COMPOUNDS AND METHODS OF USE THEREOF

-

Page/Page column 76, (2010/11/26)

The invention relates to the use of carboxyamine compounds and salts thereof in the treatment of HDAC dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases.

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