1477517-10-4Relevant academic research and scientific papers
Copper-catalyzed direct esterification of P(O)-OH compounds with phenols
Xiong, Biquan,Zeng, Kui,Zhang, Shanshan,Zhou, Yongbo,Au, Chak-Tong,Yin, Shuang-Feng
, p. 9293 - 9298 (2015)
A novel copper-catalyzed method for the direct esterification of P(O)-OH compounds using phenols as efficient esterification reagents is illustrated. It is a simple way to generate a broad spectrum of functionalized O-aryl phosphinates, phosphonates, and phosphates from basic starting materials with moderate to excellent yields.
Efficient syntheses of korupensamines A, B and michellamine B by asymmetric Suzuki-Miyaura coupling reactions
Xu, Guangqing,Fu, Wenzhen,Liu, Guodu,Senanayake, Chris H.,Tang, Wenjun
supporting information, p. 570 - 573 (2014/02/14)
Efficient asymmetric Suzuki-Miyaura coupling reactions are employed for the first time in total syntheses of chiral biaryl natural products korupensamine A and B in combination with an effective diastereoselective hydrogenation, allowing ultimately a concise and stereoselective synthesis of michellamine B. Chiral monophosphorus ligands L1-3 are effective for the syntheses of a series of functionalized chiral biaryls by asymmetric Suzuki-Miyaura coupling reactions in excellent yields and enantioselectivities (up to 99% ee). The presence of a polar-π interaction between the highly polarized BOP group and the extended π system of arylboronic acid coupling partner is believed to be important for the high enantioselectivity.
