1477517-21-7

Basic information

• Product Name: (2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-iso propyl-2,3-dihydrobenzo[d ][1,3]oxaphosphole
• Synonyms: (2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-iso propyl-2,3-dihydrobenzo[d ][1,3]oxaphosphole
• CAS NO: 1477517-21-7
• Molecular Formula: C22H29O3P
• Molecular Weight: 372.437621
• Product Categories: Chiral Phosphine
• Mol File: 1477517-21-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 451.5±45.0 °C(Predicted)
• Appearance: light-yellow/crystal
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-iso propyl-2,3-dihydrobenzo[d ][1,3]oxaphosphole(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-iso propyl-2,3-dihydrobenzo[d ][1,3]oxaphosphole(1477517-21-7)
• EPA Substance Registry System: (2S,3S)-3-(tert-butyl)-4-(2, 6-dimethoxyphenyl)-2-iso propyl-2,3-dihydrobenzo[d ][1,3]oxaphosphole(1477517-21-7)

Safety Data

• Hazardous Substances Data: 1477517-21-7(Hazardous Substances Data)

Usage

Reaction

Ligand/palladium catalyst for asymmetric Suzuki-Miyaura cross-coupling reactions.

Upstream product

• 1373432-34-8 (R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3 dihydrobenzo[d][1,3]oxaphosphole-3-oxide 
• 1477517-23-9 C₂₂H₂₉O₄P 
• 1338453-99-8 (S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2H-benzo[d][1,3]oxaphosphole 3-oxide 
• 1338453-95-4 (S)-3-tert-butyl-2,3-dihydrobenzo[d][1,3]oxaphosphol-4-yl trifluoromethanesulfonate oxide 
• 23112-96-1 (2,6-dimethoxyphenyl)boronic acid 

Relevant articles and documents

Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra- ortho-Substituted Biaryl Synthesis

Metal-catalyzed cross-coupling reactions are extensively employed in both academia and industry for the synthesis of biaryl derivatives for applications to both medicine and material science. Application of these methods to prepare tetra-ortho-substituted