147753-55-7

Upstream product

• 1222-98-6 4-nitrochalcone 
• 94547-39-4 ethyl 2-cyano-3-(4-nitrophenyl)-5-oxo-5-phenylpentanoate 
• 147753-54-6 ethyl 2-nitro-3-(4-nitrophenyl)-5-oxo-5-phenylpentanoate 

Downstream Products

• 1373319-65-3 C₁₉H₁₅NO₅ 
• 147753-57-9 ethyl 4-(4-nitrophenyl)-6-phenyl-3-pyridazinecarboxylate 
• 147753-56-8 ethyl 1,4-dihydro-4-(4-nitrophenyl)-6-phenyl-3-pyridazinecarboxylate 

Relevant academic research and scientific papers

Unexpected Iodine-Promoted Aerobic Oxidation of α-Cyano-δ-keto Esters: A Facile Synthesis of α,δ-Dicarbonyl Esters

An efficient and green method for the synthesis of various α,δ-dicarbonyl esters has been developed via a conjugate addition of ethyl cyanoacetates to chalcones and subsequent iodine-promoted aerobic oxidation. The present protocol features mild reaction

Facile regiocontrolled three-step synthesis of poly-substituted furans, pyrroles, and thiophenes: Consecutive michael addition of methyl cyanoacetate to α,β-enone, CuI-mediated aerobic oxidation, and acid-catalyzed paal-knorr synthesis

An efficient synthesis of poly-substituted furans, pyrroles, and thiophenes was carried out in a regiocontrolled manner via a three-step process; (i) conjugate addition of methyl cyanoacetate derivatives to α,β-enones, (ii) CuI-mediated aerobic oxidation,

Construction of 1,2,5-tricarbonyl compounds using methyl cyanoacetate as a glyoxylate anion synthon combined with copper(I) iodide-catalyzed aerobic oxidation

A practical and efficient synthesis of various 1,2,5-tricarbonyl compounds is described. The synthesis has been carried out by a conjugate addition of methyl cyanoacetate to the β-position of α,β-unsaturated carbonyl compounds and a subsequent copper(I) iodide-catalyzed aerobic oxidation. In addition, various α-aryl- and α-alkyl-α-keto esters have been synthesized using a similar approach. Copyright

Studies on cerebral protective agents. IV. Synthesis of novel 4-arylpyridine and 4-arylpyridazine derivatives with anti-anoxic activity

In a search for new cerebral protective agents, a series of 4-(3- or 4-nitrophenyl)-6-phenylpyridines (or pyridazines) and 2-(3-nitrophenyl)-6-phenylpyridines, possessing an amino moiety at the C-3 position of the pyridine (or pyridazine) ring, were synth