1477797-96-8Relevant articles and documents
Toward the total synthesis of divergolides C and D
Hager, Anastasia,Kuttruff, Christian A.,Hager, Dominik,Terwilliger, Daniel W.,Trauner, Dirk
supporting information, p. 1915 - 1920 (2013/09/24)
The divergolides are a family of structurally unprecedented ansa macrocycles. We describe a synthetic strategy toward divergolides C and D that hinges on the biomimetic diversification of a common intermediate. An advanced precursor that incorporates all the carbon atoms of divergolide C and D is presented, and atropisomerism in a sterically crowded acyl naphthalene is studied.