1478663-95-4 Usage
Uses
(4S)-3-[(2R)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3’R,3R,4R)-Ezetimibe (E974990), a structural analog of Ezetimibe (E975000). Ezetimibe is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
Check Digit Verification of cas no
The CAS Registry Mumber 1478663-95-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,7,8,6,6 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1478663-95:
(9*1)+(8*4)+(7*7)+(6*8)+(5*6)+(4*6)+(3*3)+(2*9)+(1*5)=224
224 % 10 = 4
So 1478663-95-4 is a valid CAS Registry Number.
1478663-95-4Relevant articles and documents
First synthesis and characterization of SRR/RSS-Ezetimibe
Ren, Yun,Li, Renjun,Deng, Yong,Guan, Mei,Wu, Yong,Hai, Li
, p. 6443 - 6446 (2013)
The two stereoisomers, SRR-Ezetimibe 2 and RSS-Ezetimibe 3 are related substances of the cholesterol absorption inhibitor drug Ezetimibe 1. Herein, we present an efficient and practical synthesis approach to deliver these two stereoisomers for the first t
